Evaluation of the Prognostic Value of Biological Markers, Coll2-1 and Coll2-1NO2 in Patients With Symptomatic Knee Osteoarthritis

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

February 28, 2019

Study Completion Date

February 28, 2019

Conditions
Knee Osteoarthritis
Interventions
OTHER

Serum and urine samples collections

Serum and urine samples will be collected at baseline, 3 month, 6 month, 12 month to assess the predictive value of cartilage-specific biomarkers Coll2-1/Coll2-1NO2 on OA progression (MRI, Clinical and radiological progression)

OTHER

Imaging (x-rays and MRI)

MRI will be done at baseline and 12 month and x-rays will be done at baseline

Trial Locations (2)

4000

University Hospital of Liege-CHU, Liège

Unknown

University Hospital of Nancy, Nancy

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Artialis

INDUSTRY

NCT02070224 - Evaluation of the Prognostic Value of Biological Markers, Coll2-1 and Coll2-1NO2 in Patients With Symptomatic Knee Osteoarthritis | Biotech Hunter | Biotech Hunter