A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

PHASE2TerminatedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

March 31, 2014

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
Hepatitis B, Chronic
Interventions
DRUG

ARC-520

DRUG

Placebo

DRUG

entecavir

DRUG

chlorpheniramine

In all cohorts, each participant received an 8 mg dose of oral chlorpheniramine 2 hours prior to each administration of ARC-520 Injection.

Trial Locations (2)

Unknown

Queen Mary Hospital, Pokfulam

Prince of Wales Hospital, Shatin

Sponsors
All Listed Sponsors
collaborator

ICON Clinical Research

INDUSTRY

lead

Arrowhead Pharmaceuticals

INDUSTRY