Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)

PHASE2CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

March 2, 2018

Study Completion Date

June 5, 2019

Conditions
Prostate Cancer
Interventions
DRUG

enzalutamide

160 mg orally once daily for six months

DRUG

Androgen Deprivation

Two injections each lasting three months, for a total of six months of androgen deprivation therapy. Doctor will help determine which androgen deprivation drug to use.

RADIATION

Radiation Therapy

Daily (Monday-Friday) for 6-8 weeks, final dose of approximately 66 Gy

Trial Locations (3)

27157

Wake Forest Baptist Health, Winston-Salem

27710

Duke University Medical Center, Durham

08903

Rutgers Cancer Institute of New Jersey, New Brunswick

Sponsors
All Listed Sponsors
collaborator

Medivation, Inc.

INDUSTRY

collaborator

Astellas Pharma Inc

INDUSTRY

lead

Duke University

OTHER