A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck

PHASE1/PHASE2UnknownINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

August 31, 2016

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2022

Conditions
Squamous Cell Carcinoma of the Head and Neck
Interventions
DRUG

Cetuximab

We will perform a randomized phase II study to investigate in first line if the addition of cetuximab to MTX is beneficial, i.e. improvement in the PFS, for the patient.

DRUG

Methotrexate

Trial Locations (8)

Unknown

Medisch Spectrum Twente, Enschede

Medical Centre Leeuwarden, Leeuwarden

Leiden University Medical Center, Leiden

Academisch Ziekenhuis Maastricht, Maastricht

Radboud university medical center, Nijmegen

Erasmus Medical Center, Rotterdam

Medical Centre Haaglanden, The Hague

St. Elisabeth Ziekenhuis, Tilburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck Serono International SA

INDUSTRY

collaborator

Leiden University Medical Center

OTHER

collaborator

Academisch Ziekenhuis Maastricht

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Medisch Spectrum Twente

OTHER

collaborator

Medical Center Haaglanden

OTHER

collaborator

Elisabeth-TweeSteden Ziekenhuis

OTHER

collaborator

Frisius Medisch Centrum

OTHER

lead

Radboud University Medical Center

OTHER