Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

PHASE3RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

December 31, 2013

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2026

Conditions
Chalazion
Interventions
DRUG

5-fluorouracil Injection

If the chalazion is present at follow-up visit, another injection of 5-FU will be given.

DRUG

Triamcinolone Acetonide

If chalazion present at follow-up, another Triamcinolone injection will be done.

PROCEDURE

Incision and Curettage

If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone/5-FU mixture.

DRUG

Triamcinolone Acetonide/5-fluorouracil mixture

If chalazion persists at follow-up visit, another injection of triamcinolone/5-FU mixture will be done.

Trial Locations (1)

98104

RECRUITING

University of Washington Eye Institute at Harborview, Seattle

All Listed Sponsors
lead

University of Washington

OTHER