A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

PHASE3CompletedINTERVENTIONAL
Enrollment

530

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

July 15, 2019

Study Completion Date

August 31, 2019

Conditions
Diabetic NephropathiesCoronary Artery Disease
Interventions
DRUG

Allopurinol

DRUG

Placebo

Inactive oral tablets identical in appearance to allopurinol tablets.

Trial Locations (30)

10029

ICAHN School of Medicine at Mount Sinai, New York

10065

Weill Cornell Medical Center, New York

10461

Albert Einstein College of Medicine / Montefiore Medical Center, The Bronx

Jacobi Medical Center, The Bronx

11501

Winthrop-University Hospital, Mineola

13210

SUNY Upstate Medical University, Syracuse

30303

Emory University - Grady Memorial Hospital, Atlanta

30318

Atlanta Diabetes Associates, Atlanta

48105

Brehm Center for Diabetes Research / University of Michigan, Ann Arbor

48202

Henry Ford Health System, Detroit

54601

Gunderson Health System, La Crosse

55455

University of Minnesota, Minneapolis

60611

Northwestern University Feinberg School of Medicine, Chicago

63110

Washington University, St Louis

75390

University of Texas Southwestern, Dallas

80045

Barbara Davis Center / University of Colorado Denver, Aurora

80231

Kaiser Permanente Colorado Institute of Health Research, Denver

98101

Virginia Mason Medical Center, Seattle

98105

University of Washington, Seattle

99204

Providence Sacred Heart Medical Center, Spokane

02114

Massachusetts General Hospital, Boston

02215

Joslin Diabetes Center, Boston

01655

University of Massachusetts Memorial Health Care, Worcester

T2T 5C7

University of Calgary, Calgary

T6G 2E1

Alberta Diabetes Institute, Edmonton

V5Y 3W2

BC Diabetes, Vancouver

M4G 3E8

LMC Diabetes and Endocrinology, Toronto

M5G 2C4

Mount Sinai Hospital / University of Toronto, Toronto

M5G 2N2

Toronto General Hospital, Toronto

DK-2820

Steno Diabetes Center, Gentofte Municipality

Sponsors
All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

Joslin Diabetes Center

OTHER

collaborator

University of Minnesota

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

University of Michigan

OTHER

collaborator

University of Toronto

OTHER

collaborator

Northwestern University Feinberg School of Medicine

OTHER

collaborator

Albert Einstein College of Medicine

OTHER

collaborator

Steno Diabetes Center Copenhagen

OTHER

collaborator

Washington University School of Medicine

OTHER

collaborator

University of Washington

OTHER

collaborator

Emory University

OTHER

collaborator

University of Calgary

OTHER

collaborator

University of Alberta

OTHER

collaborator

University of Texas Southwestern Medical Center

OTHER

collaborator

BCDiabetes.Ca

NETWORK

lead

Alessandro Doria

OTHER