A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic Therapy

PHASE3CompletedINTERVENTIONAL
Enrollment

139

Participants

Timeline

Start Date

January 31, 2014

Primary Completion Date

December 31, 2015

Study Completion Date

December 31, 2015

Conditions
Rheumatoid Arthritis
Interventions
DRUG

Tocilizumab

Tocilizumab will be administered at a dose of 162 mg as SC injection once a week.

DRUG

Methotrexate

Methotrexate will be administered at a stable dose that was initiated at least 4 weeks prior to Baseline, at investigator's discretion.

DRUG

csDMARDs

csDMARDs (at investigator's discretion) will be administered at a stable dose that was initiated at least 4 weeks prior to Baseline, at investigator's discretion.

Trial Locations (32)

13274

Marseille

13285

Marseille

14033

Caen

29609

Brest

31059

Toulouse

33076

Bordeaux

34295

Montpellier

35033

Rennes

38434

Échirolles

42277

Saint-Priest-en-Jarez

45100

La Source

46005

Cahors

54511

Vandœuvre-lès-Nancy

59037

Lille

59462

Lomme

63003

Clermont-Ferrand

67098

Strasbourg

68070

Mulhouse

69437

Lyon

72037

Le Mans

74203

Thonon-les-Bains

74370

Metz-Tessy

75475

Paris

75571

Paris

75651

Paris

75679

Paris

75877

Paris

76031

Rouen

80054

Amiens

87042

Limoges

94163

Saint-Mandé

98012

Monaco

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT02001987 - A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic Therapy | Biotech Hunter | Biotech Hunter