A Phase III Randomised Trial of Peri-Operative Chemotherapy Versus sUrveillance in Upper Tract Urothelial Cancer (POUT)

PHASE3UnknownINTERVENTIONAL
Enrollment

261

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

November 7, 2018

Study Completion Date

May 31, 2022

Conditions
Transitional Cell Carcinoma of Ureter
Interventions
DRUG

Chemotherapy

OTHER

Surveillance

Patients will be closely monitored for early signs of recurrence, for which they will receive treatment as decided in discussion between the clinician and patient. This may include chemotherapy.

Trial Locations (61)

TN24 0LZ

William Harvey Hospital, Ashford-Kent

EX31 4JB

North Devon District Hospital, Barnstaple

SS16 5NL

Basildon University Hospital, Basildon

CT2 3NG

Kent and Canterbury Hospital, Canterbury

NW3 2QG

Royal Free Hospital, Hampstead, London

IP4 5PD

Ipswich Hospital NHS Trust, Ipswich

LS9 7TF

St. James's University Hospital, Leeds

EC1M 6BQ

Barts and the London School of Medicine, London

ME16 9QQ

Maidstone Hospital, Maidstone

M20 4BX

Christie Hospital NHS Trust, Manchester

CT9 4AN

Queen Elizabeth The Queen Mother Hospital, Margate

CH63 4JY

Clatterbridge Centre for Oncology NHS Trust, Merseyside

NG5 1PB

Nottingham City Hospital NHS Trust, Nottingham

PE3 6DA

Peterborough Hospitals Trust, Peterborough

PR2 9HT

Rosemere Cancer Centre at Royal Preston Hospital, Preston

S1O 2SJ

Cancer Research Centre at Weston Park Hospital, Sheffield

SM2 5PT

Royal Marsden Hosital, Sutton, Surrey

The Royal Marsden Hospital, Sutton

SS0 0RY

Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea

WV10 0QP

New Cross Hospital, Wolverhampton

KA6 6DX

Ayr Hospital, Ayr

CF14 2TL

Velindre Cancer Center at Velinde Hospital, Cardiff

SA 2 8QA

Singleton Hospital, Swansea

Unknown

Bristol Haematology and Oncology Centre, Bristol

Southmead Hospital, Bristol

University Hospitals Coventry and Warwickshire NHS Trust, Coventry

Darent Valley Hospital, Dartford

Royal Derby Hospital, Derby

Royal Bournemouth General Hospital, Dorset

Royal Devon and Exeter Hospital, Exeter

Beatson West of Scotland Cancer Centre, Glasgow

Calderdale Royal Infirmary, Halifax

Huddersfield Royal Infirmary, Huddersfield

Leicester Royal Infirmary, Leicester

Charing Cross Hospital, London

Northwick Park Hospital, London

James Cook University Hospital, Middlesbrough

Freeman Hospital, Newcastle upon Tyne

Queen Alexandra Hospital,, Portsmouth

Queen's Hospital,, Romford, Essex

Southampton General Hospital, Southampton

Musgrove Park Hospital, Taunton

SW3 6JJ

Royal Marsden Hospital, Chelsea

EH4 2XU

Western General Hospital, Edinburgh

GU2 7XX

Royal Surrey County Hospital, Guildford

IV2 3UJ

Caithness General Hospital, Inverness

Raigmore Hospital, Inverness

LN2 5QY

Lincoln County Hospital, Lincoln

L7 8XP

Royal Liverpool University Hospital, Liverpool

SE1 9RT

Guy's Hospital, London

M13 9WL

Manchester Royal Infirmary, Manchester

NR4 7UY

Norfolk and Norwich University Hospital, Norwich

LL18 5UJ

Glan Clywd Hospital, Rhyl

SY3 8XQ

Royal Shrewsbury Hospital, Shrewsbury

SG1 4AA

Lister Hospital, Stevenage

TS19 8PE

University Hospital of North Tees, Stockton-on-Tees

GU16 7UJ

Frimley Park Hospital, Surrey

TQ2 7AA

Torbay District General Hospital, Torbay

TR1 3LJ

Royal Cornwall Hospital, Treliske

BN11 2DH

Worthing Hospital, Worthing

YO31 8HE

York District Hospital, York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cancer Research UK

OTHER

lead

Institute of Cancer Research, United Kingdom

OTHER