Mojito Study (Mashed Or Just Integral Pill of TicagrelOr ? )

PHASE3CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

March 31, 2014

Study Completion Date

April 30, 2014

Conditions
Acute Coronary SyndromeAdverse Reaction to Antiplatelet Agent
Interventions
DRUG

Ticagrelor mashed pills

The loading dose will be performed as soon as possible in the Emergency Room or in the Cath Lab. In all case before the end of the PCI (percutaneous coronary intervention) . In the case of vomit in the first hour after drug loading dose a new reduced loading dose will be administered (90 mg Ticagrelor). Mashed pills administration will be prepared placing 2 ticagrelor pills in a mortar and mashing for 60 seconds using a pestle. The total contents of the mortar will be transferred to the dosing cup, 50 mL of purify water will be added, and the suspension mixed up before drinking. Afterwards, 100 mL of purify water will be administered to the patient.

DRUG

Ticagrelor integral pills

The loading dose will be performed as soon as possible in the Emergency Room or in the Cath Lab. In all case before the end of the PCI (percutaneous coronary intervention) . In the case of vomit in the first hour after drug loading dose a new reduced loading dose will be administered (90 mg Ticagrelor).

Trial Locations (2)

Unknown

Department of Cardiology, Patras University Hospital, Pátrai

Careggi Hospital, Florence

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

collaborator

A.R. CARD Onlus Foundation

OTHER

lead

David Antoniucci

OTHER