Modafinil and Cognitive Function in POTS

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Postural Tachycardia Syndrome
Interventions
DRUG

Placebo

Locking gelatin capsules filled with microcrystalline cellulose

DRUG

Modafinil

Modafinil is a wakefulness-promoting or psychostimulant drug. It will be administered as a single 200 mg oral tablet.

DRUG

Propranolol

Propranolol is a non-selective beta adrenergic antagonist.It will be administered as a single 20 mg oral tablet.

Trial Locations (1)

37211

Vanderbilt University, Nashville

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

Vanderbilt University Medical Center

OTHER