Effect of Glucose on QTc Interval in Type 1 Diabetes

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

February 10, 2019

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Diabetes
Interventions
DRUG

Moxifloxacin

"1. a single oral dose of 400mg Moxifloxacin plus a hyper-glycaemic clamp for 4 hours~2. a single oral dose of 400mg Moxifloxacin plus C-peptide~3. a single oral dose of 400mg Moxifloxacin~4. placebo~Oral doses of placebo and moxifloxacin will be administered by a Research Physician or Pharmacy staff member between 08:00 a.m. and 10:00 a.m."

OTHER

hyper-glycaemic clamp

a hyper-glycaemic clamp only for 2 hours followed by a hyper-glycaemic clamp plus C-peptide for 2 hours

Trial Locations (1)

SE1 1YR

Richmond Pharmacology Ltd. 1a Newcomen St, London Bridge, London

All Listed Sponsors
collaborator

Richmond Pharmacology Limited

INDUSTRY

lead

Richmond Research Institute

INDUSTRY

NCT01984827 - Effect of Glucose on QTc Interval in Type 1 Diabetes | Biotech Hunter | Biotech Hunter