NCT01930188View on ClinicalTrials.gov

Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes

PHASE3CompletedINTERVENTIONAL
Enrollment

1,231

Participants

Timeline

Start Date

December 2, 2013

Primary Completion Date

October 12, 2015

Study Completion Date

October 12, 2015

Conditions
DiabetesDiabetes Mellitus, Type 2
Interventions
DRUG

semaglutide

For subcutaneous injection (s.c., under the skin) once weekly. Will follow a fixed dose escalation regimen. The trial drug will be added on to the subject's stable pre-trial medication.

DRUG

sitagliptin

Tablets for oral administration once daily. The trial drug will be added on to the subject's stable pre-trial medication.

DRUG

placebo

Tablets for oral administration once daily. The trial drug will be added on to the subject's stable pre-trial medication.

DRUG

placebo

For subcutaneous injection (s.c., under the skin) once weekly. Will follow a fixed dose escalation regimen. The trial drug will be added on to the subject's stable pre-trial medication.

Trial Locations (141)

1076

Novo Nordisk Investigational Site, Budapest

1233

Novo Nordisk Investigational Site, Sofia

1336

Novo Nordisk Investigational Site, Sofia

1739

Novo Nordisk Investigational Site, Krugersdorp

2001

Novo Nordisk Investigational Site, Johannesburg

2040

Novo Nordisk Investigational Site, Kløfta

2212

Novo Nordisk Investigational Site, Kongsvinger

2317

Novo Nordisk Investigational Site, Hamar

2850

Novo Nordisk Investigational Site, Petrich

3001

Novo Nordisk Investigational Site, Vratsa

4001

Novo Nordisk Investigational Site, Durban

4005

Novo Nordisk Investigational Site, Stavanger

4043

Novo Nordisk Investigational Site, Debrecen

4092

Novo Nordisk Investigational Site, Durban

4700

Novo Nordisk Investigational Site, Smolyan

5201

Novo Nordisk Investigational Site, East London

6000

Novo Nordisk Investigational Site, Stara Zagora

6003

Novo Nordisk Investigational Site, Ålesund

6300

Novo Nordisk Investigational Site, Haskovo

7000

Novo Nordisk Investigational Site, Rousse

8000

Novo Nordisk Investigational Site, Burgas

8800

Novo Nordisk Investigational Site, Sliven

9301

Novo Nordisk Investigational Site, Bloemfontein

10330

Novo Nordisk Investigational Site, Bangkok

10400

Novo Nordisk Investigational Site, Bangkok

10700

Novo Nordisk Investigational Site, Bangkoknoi, Bangkok

15006

Novo Nordisk Investigational Site, A Coruña

18009

Novo Nordisk Investigational Site, Cherkasy

19200

Novo Nordisk Investigational Site, Çorum

20129

Novo Nordisk Investigational Site, Aguascalientes

20230

Novo Nordisk Investigational Site, Aguascalientes

21010

Novo Nordisk Investigational Site, Vinnytsia

25198

Novo Nordisk Investigational Site, Lleida

30000

Novo Nordisk Investigational Site, Nakhon Ratchasima

34303

Novo Nordisk Investigational Site, Istanbul

34371

Novo Nordisk Investigational Site, Istanbul

34718

Novo Nordisk Investigational Site, Istanbul

34722

Novo Nordisk Investigational Site, Istanbul

34752

Novo Nordisk Investigational Site, Istanbul

34890

Novo Nordisk Investigational Site, Istanbul

41003

Novo Nordisk Investigational Site, Seville

42084

Novo Nordisk Investigational Site, Pachuca

42090

Novo Nordisk Investigational Site, Konya

44670

Novo Nordisk Investigational Site, Guadalajara

53020

Novo Nordisk Investigational Site, Rize

61040

Novo Nordisk Investigational Site, Trabzon

64620

Novo Nordisk Investigational Site, Monterrey

65114

Novo Nordisk Investigational Site, Odesa

69600

Novo Nordisk Investigational Site, Zaporizhia

76018

Novo Nordisk Investigational Site, Ivano-Frankivsk

100342

Novo Nordisk Investigational Site, Ploieşti

110017

Novo Nordisk Investigational Site, New Delhi

115478

Novo Nordisk Investigational Site, Moscow

117036

Novo Nordisk Investigational Site, Moscow

119435

Novo Nordisk Investigational Site, Moscow

125367

Novo Nordisk Investigational Site, Moscow

141001

Novo Nordisk Investigational Site, Ludhiana

150003

Novo Nordisk Investigational Site, Yaroslavl

197762

Novo Nordisk Investigational Site, Saint Petersburg

214019

Novo Nordisk Investigational Site, Smolensk

302004

Novo Nordisk Investigational Site, Jaipur

380006

Novo Nordisk Investigational Site, Ahmedabad

394018

Novo Nordisk Investigational Site, Voronezh

400008

Novo Nordisk Investigational Site, Mumbai

400138

Novo Nordisk Investigational Site, Volgograd

410018

Novo Nordisk Investigational Site, Saratov

411001

Novo Nordisk Investigational Site, Pune

411004

Novo Nordisk Investigational Site, Pune

411040

Novo Nordisk Investigational Site, Pune

430123

Novo Nordisk Investigational Site, Baia Mare

443041

Novo Nordisk Investigational Site, Samara

450083

Novo Nordisk Investigational Site, Ufa

452010

Novo Nordisk Investigational Site, Indore

500003

Novo Nordisk Investigational Site, Hyderabad

500365

Novo Nordisk Investigational Site, Brasov

560034

Novo Nordisk Investigational Site, Bangalore

560054

Novo Nordisk Investigational Site, Bangalore

600116

Novo Nordisk Investigational Site, Chennai

603011

Novo Nordisk Investigational Site, Nizhny Novgorod

625023

Novo Nordisk Investigational Site, Tyumen

630047

Novo Nordisk Investigational Site, Novosibirsk

630099

Novo Nordisk Investigational Site, Novosibirsk

634063

Novo Nordisk Investigational Site, Tomsk

656024

Novo Nordisk Investigational Site, Barnaul

673017

Novo Nordisk Investigational Site, Kozhikode

682041

Novo Nordisk Investigational Site, Kochi

695011

Novo Nordisk Investigational Site, Trivandrum

700020

Novo Nordisk Investigational Site, Kolkata

700054

Novo Nordisk Investigational Site, Kolkata

751019

Novo Nordisk Investigational Site, Bhubaneswar

C1425AGC

Novo Nordisk Investigational Site, Buenos Aires

C1179AAB

Novo Nordisk Investigational Site, CABA

Unknown

Novo Nordisk Investigational Site, CABA

Novo Nordisk Investigational Site, Shatin, New Territories

Novo Nordisk Investigational Site, Osaka-shi, Osaka

Novo Nordisk Investigational Site, Moscow

B7600GNY

Novo Nordisk Investigational Site, Mar del Plata

537 01

Novo Nordisk Investigational Site, Chrudim

707 02

Novo Nordisk Investigational Site, Ostrava

304 60

Novo Nordisk Investigational Site, Pilsen

150 00

Novo Nordisk Investigational Site, Prague

149 00

Novo Nordisk Investigational Site, Praha 4- Chodov

H-1134

Novo Nordisk Investigational Site, Budapest

H-6720

Novo Nordisk Investigational Site, Szeged

H-9700

Novo Nordisk Investigational Site, Szombathely

070-0002

Novo Nordisk Investigational Site, Asahikawa-shi, Hokkaido

311-0113

Novo Nordisk Investigational Site, Ibaraki

582-0005

Novo Nordisk Investigational Site, Kashiwara-shi, Osaka

800 0252

Novo Nordisk Investigational Site, Kitakyushu-shi, Fukuoka

181-0013

Novo Nordisk Investigational Site, Mitaka-shi, Tokyo

310-0826

Novo Nordisk Investigational Site, Mito-shi, Ibaraki

880-0034

Novo Nordisk Investigational Site, Miyazaki

700 8505

Novo Nordisk Investigational Site, Okayama-shi, Okayama

569-1045

Novo Nordisk Investigational Site, Osaka

532 0003

Novo Nordisk Investigational Site, Osaka-shi, Osaka

060-0001

Novo Nordisk Investigational Site, Sapporo-shi, Hokkaido

103-0027

Novo Nordisk Investigational Site, Tokyo

125-0054

Novo Nordisk Investigational Site, Tokyo

2805-267

Novo Nordisk Investigational Site, Almada

3046-853

Novo Nordisk Investigational Site, Coimbra

1250-230

Novo Nordisk Investigational Site, Lisbon

1500-650

Novo Nordisk Investigational Site, Lisbon

4464-513

Novo Nordisk Investigational Site, Matosinhos Municipality

2304-909

Novo Nordisk Investigational Site, Tomar

4901-858

Novo Nordisk Investigational Site, Viana do Castelo

4434-502

Novo Nordisk Investigational Site, Vila Nova de Gaia

020359

Novo Nordisk Investigational Site, Bucharest

022441

Novo Nordisk Investigational Site, Bucharest

0002

Novo Nordisk Investigational Site, Pretoria

0084

Novo Nordisk Investigational Site, Pretoria

04001

Novo Nordisk Investigational Site, Almería

08540

Novo Nordisk Investigational Site, Centelles (Barcelona)

08430

Novo Nordisk Investigational Site, La Roca Del Vallés

07010

Novo Nordisk Investigational Site, Palma de Mallorca

291 85

Novo Nordisk Investigational Site, Kristianstad

222 22

Novo Nordisk Investigational Site, Lund

205 02

Novo Nordisk Investigational Site, Malmo

113 24

Novo Nordisk Investigational Site, Stockholm

06110

Novo Nordisk Investigational Site, Ankara

07058

Novo Nordisk Investigational Site, Antalya

04114

Novo Nordisk Investigational Site, Kyiv

Sponsors

Lead Sponsor

Novo Nordisk A/S
All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY

NCT01930188 - Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes | Biotech Hunter | Biotech Hunter