Increased Activity of a Renal Salt Transporter (ENaC) in Diabetic Kidney Disease

NAUnknownINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

October 31, 2013

Primary Completion Date

December 31, 2014

Conditions
Diabetic NephropathiesHypertension
Interventions
DIETARY_SUPPLEMENT

Standardized salt diet

200 mmol NaCl per day given as three meals daily for 4 consecutive days.

DRUG

Amiloride

Amiloride tablet 20 mg two times daily (morning and afternoon) for two consecutive days.

Trial Locations (1)

DK-5000

Cardiovascular and Renal Research, Odense

Sponsors

Collaborators (1)

All Listed Sponsors
lead

University of Southern Denmark

OTHER

collaborator

Odense University Hospital

OTHER

collaborator

Region of Southern Denmark

OTHER

collaborator

The Ministry of Science, Technology and Innovation, Denmark

OTHER_GOV

collaborator

Danish Heart Foundation

OTHER