An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

PHASE2CompletedINTERVENTIONAL
Enrollment

257

Participants

Timeline

Start Date

June 30, 2013

Primary Completion Date

December 31, 2014

Study Completion Date

May 31, 2015

Conditions
Rheumatoid Arthritis
Interventions
DRUG

Placebo

Placebo subcutaneous injections (SC) every 4 weeks through Week 12

DRUG

CNTO 6785 200 mg

CNTO 6785 200 mg SC every 4 weeks from Week 16 through Week 28

DRUG

CNTO 6785 200 mg

CNTO 6785 200 mg SC every 4 weeks through Week 28

DRUG

CNTO 6785 100 mg

CNTO 6785 100 mg SC every 4 weeks through Week 28

DRUG

CNTO 6785 50 mg

CNTO 6785 50 mg SC every 4 weeks through Week 28

DRUG

CNTO 6785 15 mg

CNTO 6785 15 mg SC every 4 weeks through Week 28

DRUG

Methotrexate (MTX)

MTX at the same stable dose through Week 32, that participants were receiving prior to screening.

Trial Locations (32)

Unknown

Buenos Aires

Ciudad Autonoma Buenos Aires

Córdoba

La Capital

San Juan

Barranquilla

Bogotá

Medellín

Jihlava

Prague

Cebu

Iloilo City

Lipa City

Quezon City

Bydgoszcz

Grodzisk Mazowiecki

Lodz

Lublin

Poznan

Warsaw

Wroclaw

Barnaul

Kemerovo

Kursk

Moscow

Novosibirsk

Petrozavodsk

Saint Petersburg

Yaroslavl

Yekaterinburg

Bangkok

Chiang Mai

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT01909427 - An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy | Biotech Hunter | Biotech Hunter