NCT01907854 - Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin | Biotech Hunter

Enrollment

407

Participants

Timeline

Start Date

December 2, 2013

Primary Completion Date

June 15, 2015

Study Completion Date

June 15, 2015

Conditions

DiabetesDiabetes Mellitus, Type 2

Interventions

DRUG

liraglutide

Starting dose of 0.6 mg/day, with weekly dose escalations of 0.6 mg/day until the maintenance dose of 1.8 mg/day is reached. Administered subcutaneously (s.c., under the skin) once daily + metformin tablets (at least 1000 mg/day)

DRUG

sitagliptin

100 mg/day sitagliptin tablets once-daily + metformin (at least 1000 mg/day)

DRUG

placebo

Sitagliptin placebo tablets once-daily

DRUG

placebo

Sitagliptin placebo tablets once-daily

Trial Locations (106)

1042

Novo Nordisk Investigational Site, Budapest

2800

Novo Nordisk Investigational Site, Tatabánya

3100

Novo Nordisk Investigational Site, Salgótarján

3300

Novo Nordisk Investigational Site, Eger

4043

Novo Nordisk Investigational Site, Debrecen

9400

Novo Nordisk Investigational Site, Sopron

11540

Novo Nordisk Investigational Site, Sanlúcar de Barrameda

12206

Novo Nordisk Investigational Site, Albany

15405

Novo Nordisk Investigational Site, Ferrol

18003

Novo Nordisk Investigational Site, Granada

19606

Novo Nordisk Investigational Site, Reading

22100

Novo Nordisk Investigational Site, Nahariya

23454

Novo Nordisk Investigational Site, Virginia Beach

28144

Novo Nordisk Investigational Site, Salisbury

28210

Novo Nordisk Investigational Site, Charlotte

29006

Novo Nordisk Investigational Site, Málaga

29118

Novo Nordisk Investigational Site, Orangeburg

29461

Novo Nordisk Investigational Site, Moncks Corner

30097

Novo Nordisk Investigational Site, Johns Creek

32207

Novo Nordisk Investigational Site, Jacksonville

32216

Novo Nordisk Investigational Site, Jacksonville

32258

Novo Nordisk Investigational Site, Jacksonville

32626

Novo Nordisk Investigational Site, Chiefland

33012

Novo Nordisk Investigational Site, Hialeah

33181

Novo Nordisk Investigational Site, North Miami

33183

Novo Nordisk Investigational Site, Miami

33308

Novo Nordisk Investigational Site, Fort Lauderdale

33952

Novo Nordisk Investigational Site, Port Charlotte

35152

Novo Nordisk Investigational Site, Haifa

38119

Novo Nordisk Investigational Site, Memphis

41009

Novo Nordisk Investigational Site, Seville

44281

Novo Nordisk Investigational Site, Kfar Saba

44311

Novo Nordisk Investigational Site, Akron

46123

Novo Nordisk Investigational Site, Avon

46851

Novo Nordisk Investigational Site, Herzliya

47714

Novo Nordisk Investigational Site, Evansville

47725

Novo Nordisk Investigational Site, Evansville

51501

Novo Nordisk Investigational Site, Council Bluffs

60077

Novo Nordisk Investigational Site, Skokie

60604

Novo Nordisk Investigational Site, Chicago

61602

Novo Nordisk Investigational Site, Peoria

62038

Novo Nordisk Investigational Site, Tel Aviv

63376

Novo Nordisk Investigational Site, City of Saint Peters

76104

Novo Nordisk Investigational Site, Fort Worth

76180

Novo Nordisk Investigational Site, North Richland Hills

77024

Novo Nordisk Investigational Site, Houston

77030

Novo Nordisk Investigational Site, Houston

77036

Novo Nordisk Investigational Site, Houston

77079

Novo Nordisk Investigational Site, Houston

77478

Novo Nordisk Investigational Site, Sugar Land

78130

Novo Nordisk Investigational Site, New Braunfels

78245

Novo Nordisk Investigational Site, San Antonio

78539

Novo Nordisk Investigational Site, Edinburg

79707

Novo Nordisk Investigational Site, Midland

80909

Novo Nordisk Investigational Site, Colorado Springs

80922

Novo Nordisk Investigational Site, Colorado Springs

83221

Novo Nordisk Investigational Site, Blackfoot

85018

Novo Nordisk Investigational Site, Phoenix

85027

Novo Nordisk Investigational Site, Phoenix

85704

Novo Nordisk Investigational Site, Tucson

85724

Novo Nordisk Investigational Site, Tucson

87520

Novo Nordisk Investigational Site, Ofakim

89119

Novo Nordisk Investigational Site, Las Vegas

92025

Novo Nordisk Investigational Site, Escondido

92691

Novo Nordisk Investigational Site, Mission Viejo

95661

Novo Nordisk Investigational Site, Roseville

96814

Novo Nordisk Investigational Site, Honolulu

110060

Novo Nordisk Investigational Site, New Delhi

380008

Novo Nordisk Investigational Site, Ahmedabad

382428

Novo Nordisk Investigational Site, Gandhinagar

400007

Novo Nordisk Investigational Site, Mumbai

411040

Novo Nordisk Investigational Site, Pune

500082

Novo Nordisk Investigational Site, Hyderabad

530002

Novo Nordisk Investigational Site, Visakhapatnam

560002

Novo Nordisk Investigational Site, Bangalore

3339419

Novo Nordisk Investigational Site, Haifa

6937947

Novo Nordisk Investigational Site, Tel Aviv

60005-4144

Novo Nordisk Investigational Site, Arlington Heights

04401

Novo Nordisk Investigational Site, Bangor

02720

Novo Nordisk Investigational Site, Fall River

48085-5524

Novo Nordisk Investigational Site, Troy

03063

Novo Nordisk Investigational Site, Nashua

08009

Novo Nordisk Investigational Site, Berlin

07202

Novo Nordisk Investigational Site, Elizabeth

99202-3649

Novo Nordisk Investigational Site, Spokane

V3S 2N6

Novo Nordisk Investigational Site, Surrey

L6S 0C6

Novo Nordisk Investigational Site, Brampton

L7M 4Y1

Novo Nordisk Investigational Site, Burlington

L4K 4M2

Novo Nordisk Investigational Site, Concord

M9R 4E1

Novo Nordisk Investigational Site, Etobicoke

L3M 1P3

Novo Nordisk Investigational Site, Grimsby

K1K 4L2

Novo Nordisk Investigational Site, Ottawa

N7T 4X3

Novo Nordisk Investigational Site, Sarnia

N7G 1Y7

Novo Nordisk Investigational Site, Strathroy

M3J 1N2

Novo Nordisk Investigational Site, Toronto

M4G 3E8

Novo Nordisk Investigational Site, Toronto

M9V 4B4

Novo Nordisk Investigational Site, Toronto

J2B 7T1

Novo Nordisk Investigational Site, Drummondville

H4A 3T2

Novo Nordisk Investigational Site, Montreal

G6W 5M6

Novo Nordisk Investigational Site, Saint Romuald

G8T 7A1

Novo Nordisk Investigational Site, Trois-Rivières

G3K 2P8

Novo Nordisk Investigational Site, Québec

H-5700

Novo Nordisk Investigational Site, Gyula

H-6720

Novo Nordisk Investigational Site, Szeged

00921

Novo Nordisk Investigational Site, San Juan

08916

Novo Nordisk Investigational Site, Badalona