A Safety Study of SGN-CD33A in AML Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

195

Participants

Timeline

Start Date

July 31, 2013

Primary Completion Date

March 18, 2016

Study Completion Date

December 8, 2017

Conditions
Acute Myelogenous LeukemiaAcute Myeloid LeukemiaAcute Promyelocytic Leukemia
Interventions
DRUG

HMA

azacitidine 75 mg/m2 for 7 days or decitabine 20mg/m2 for 5 days

DRUG

SGN-CD33A

Given intravenously on Day 1 or Days 1 and 4 every 3 weeks (SGN-CD33A Monotherapy) or given intravenously on the final HMA dosing day every 4 weeks (SGN-CD33A+HMA)

Trial Locations (14)

10021

Memorial Sloan Kettering Cancer Center, New York

30322

Winship Cancer Institute / Emory University School of Medicine, Atlanta

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

35294

University of Alabama at Birmingham, Birmingham

44195

Cleveland Clinic, The, Cleveland

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor

75246

Charles A. Sammons Cancer Center / Baylor University Medical Center, Dallas

84112

University of Utah, Salt Lake City

91010-3000

City of Hope National Medical Center, Duarte

02114

Massachusetts General Hospital, Boston

02215

Dana Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

77030-4095

MD Anderson Cancer Center / University of Texas, Houston

98109-1024

Fred Hutchinson Cancer Research Center, Seattle

All Listed Sponsors
lead

Seagen Inc.

INDUSTRY

NCT01902329 - A Safety Study of SGN-CD33A in AML Patients | Biotech Hunter | Biotech Hunter