HALT Progression of Polycystic Kidney Disease Study B

PHASE3CompletedINTERVENTIONAL
Enrollment

486

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
Kidney, Polycystic
Interventions
DRUG

Lisinopril

Lisinopril titrated to 5mg, 10mg, 20mg, 40mg as tolerated by participants, to achieve standard blood pressure control of 110-130/80 mm Hg.

DRUG

Telmisartan

Telmisartan titrated to 40mg and 80mg, as tolerated by participants, to achieve standard blood pressure control of 110-130/80 mm Hg.

DRUG

Placebo

Placebo titrated to 40mg and 80mg, as tolerated by participants, to achieve standard blood pressure control of 110-130/80 mm Hg.

Trial Locations (7)

30322

Emory University School of Medicine, Atlanta

44195

Cleveland Clinic Foundation, Cleveland

55905

Mayo Clinic, Rochester

66160

University of Kansas Medical Center, Kansas City

800045

University of Colorado Health Sciences Center, Aurora

02111

Tufts University-New England Medical Center, Boston

02215

Beth Israel Deaconess Medical Center, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Boehringer Ingelheim

INDUSTRY

collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Polycystic Kidney Disease Foundation

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

Washington University School of Medicine

OTHER

lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

NCT01885559 - HALT Progression of Polycystic Kidney Disease Study B | Biotech Hunter | Biotech Hunter