101
Participants
Start Date
July 31, 2013
Primary Completion Date
June 30, 2015
Study Completion Date
June 30, 2015
Combined epidural-general anesthesia (CEGA)
Combined epidural-general anesthesia (CEGA) will be used intraoperatively and patient-controlled epidural analgesia (PCEA) will be used postoperatively in a multimodal analgesic regimen.
Volulyte® (6% HES 130/0.4 in balanced solution)
"For the SOC Group: Intraoperative fluid management includes Volulyte® (6% HES 130/0.4 in balanced solution) as the only colloid solution to be used, the daily dosage of Volulyte® is restricted to 50 ml/kg.~For the ERS Group:~GDFT regimen will be utilized using Volulyte® (6% HES 130/0.4 in balanced solution) during surgery. The daily dosage of Volulyte® is restricted to 50 ml/kg."
Patient-Controlled Epidural Analgesia (PCEA)
For the ERS Group, patient-controlled epidural analgesia (PCEA) will be used postoperatively in a multimodal analgesic regimen.
Samsung Medical Center, Gangnam-Gu
Yonsei University College of Medicine, Seodaemun-gu
Asan Medical Center, Songpa-gu
Lead Sponsor
Duke University
OTHER