30
Participants
Start Date
October 31, 2013
Primary Completion Date
July 31, 2016
Study Completion Date
July 31, 2016
Intravenous immunoglobulin (IVIG)
All participants will receive the same dose of IVIG at the same intervals in an open-label fashion as long as the subject does not have any increased risk for toxicity for any IVIG infusion. IVIG will be initiated on day 3 (up to day 5) after HPE surgery (HPE is day 0) at a dose of 1 gm/kg body weight by slow intravenous infusion over at least 4 hours. The same dose (1 gm/kg) and duration of infusion will be repeated on day 30 and day 60 after HPE.
Children's Hospital at Pittsburgh, Pittsburgh
Children's Hospital of Philadelphia, Philadelphia
Children's Healthcare of Atlanta, Atlanta
Children's Hospital Medical Center, Cincinnati
Children's Hospital Colorado, Aurora
Children's Hospital Los Angeles, Los Angeles
Hospital for Sick Children, Toronto
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH