Phase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067)

PHASE3CompletedINTERVENTIONAL
Enrollment

945

Participants

Timeline

Start Date

June 11, 2013

Primary Completion Date

August 1, 2016

Study Completion Date

April 19, 2024

Conditions
Unresectable or Metastatic Melanoma
Interventions
BIOLOGICAL

Nivolumab

BIOLOGICAL

Ipilimumab

BIOLOGICAL

Placebo for Nivolumab

BIOLOGICAL

Placebo for Ipilimumab

Trial Locations (150)

0

Local Institution - 0032, Galway

7

Local Institution - 0036, Dublin

1011

Local Institution - 0189, Lausanne

1090

Local Institution - 0145, Vienna

Local Institution - 0003, Brussels

1142

Local Institution - 0029, Auckland

1200

Local Institution - 0002, Brussels

1211

Local Institution - 0164, Geneva

2050

Local Institution - 0017, Camperdown

2060

Local Institution - 0138, North Sydney

2109

Local Institution - 0023, Macquarie University

2290

Local Institution - 0028, Gateshead

2450

Local Institution - 0031, Coffs Harbour

2650

Local Institution - 0004, Edegem

2730

Local Institution - 0078, Herlev

3000

Local Institution - 0026, Melbourne

Local Institution - 0103, Leuven

3084

Local Institution - 0016, Heidelberg

3128

Local Institution - 0024, Box Hill

4102

Local Institution - 0018, Woolloongabba

4120

Local Institution - 0019, Brisbane

4215

Local Institution - 0022, Southport

5000

Local Institution - 0020, Adelaide

Local Institution - 0077, Odense

5020

Local Institution - 0148, Salzburg

5037

Local Institution - 0025, Kurralta Park

6009

Local Institution - 0021, Nedlands

8091

Local Institution - 0163, Zurich

8200

Local Institution - 0076, Aarhus

9000

Local Institution - 0005, Ghent

9007

Local Institution - 0186, Sankt Gallen

10016

Local Institution - 0174, New York

10020

Local Institution - 0070, New York

12206

Local Institution - 0079, Albany

13385

Local Institution - 0126, Marseille

15232

Local Institution - 0069, Pittsburgh

16132

Local Institution - 0115, Genova

18015

Local Institution - 0112, Bethlehem

18102

Local Institution - 0061, Allentown

20007

Local Institution - 0098, Washington D.C.

20010

Local Institution - 0183, Washington D.C.

20133

Local Institution - 0172, Milan

20141

Local Institution - 0117, Milan

21093

Local Institution - 0080, Lutherville

21614

Local Institution - 0162, Buxtehude

24105

Local Institution - 0158, Kiel

24127

Local Institution - 0176, Bergamo

27710

Local Institution - 0048, Durham

28007

Local Institution - 0150, Madrid

28046

Local Institution - 0149, Madrid

28204

Local Institution - 0047, Charlotte

29010

Local Institution - 0153, Málaga

29605

Local Institution - 0154, Greenville

30322

Local Institution - 0051, Atlanta

30625

Local Institution - 0159, Hanover

31008

Local Institution - 0147, Pamplona

32207

Local Institution - 0042, Jacksonville

32806

Local Institution - 0008, Orlando

33521

Local Institution - 0169, Tampere

35042

Local Institution - 0127, Rennes

37203

Local Institution - 0062, Nashville

37232

Local Institution - 0064, Nashville

39216

Local Institution - 0065, Jackson

44093

Local Institution - 0056, Nantes

44106

Local Institution - 0007, Cleveland

45147

Local Institution - 0156, Essen

47014

Local Institution - 0113, Meldola (FC)

48109

Local Institution - 0087, Ann Arbor

52621

Local Institution - 0121, Tel Litwinsky

53100

Local Institution - 0116, Siena

55407

Local Institution - 0187, Minneapolis

63110

Local Institution - 0067, St Louis

69120

Local Institution - 0157, Heidelberg

69310

Local Institution - 0124, Pierre-Bénite

72076

Local Institution - 0134, Tübingen

75246

Local Institution - 0044, Dallas

Texas Oncology, Dallas

75475

Local Institution - 0058, Paris

77210

Local Institution - 0088, Houston

80045

Local Institution - 0052, Aurora

80131

Local Institution - 0114, Napoli

80337

Local Institution - 0160, München

84112

Local Institution - 0089, Salt Lake City

85234

Local Institution - 0085, Gilbert

85724

University of Arizona Cancer Center, Tucson

87106

Local Institution - 0068, Albuquerque

89148

Local Institution - 0015, Las Vegas

90025

Local Institution - 0053, Los Angeles

90095

Local Institution - 0014, Los Angeles

91054

Local Institution - 0171, Erlangen

91120

Local Institution - 0120, Jerusalem

92104

Local Institution - 0125, Boulogne-Billancourt

92262

Comprehensive Cancer Center At Desert Regional Medical Ctr, Palm Springs

92270

Local Institution - 0066, Rancho Mirage

94115

California Pacific Medical Center Research Institute, San Francisco

94143

Local Institution - 0049, San Francisco

94805

Local Institution, Villejuif

97213

Local Institution - 0045, Portland

98109

Local Institution - 0054, Seattle

99089

Local Institution - 0161, Erfurt

115478

Local Institution - 0130, Moscow

197758

Local Institution - 0132, Saint Petersburg

198255

Local Institution - 0128, Saint Petersburg

443031

Local Institution - 0131, Samara

92093-0698

Local Institution - 0046, La Jolla

06520

Local Institution - 0084, New Haven

04074

Maine Center For Cancer Medicine, Scarborough

02215

Local Institution - 0081, Boston

Local Institution - 0082, Boston

Local Institution - 0083, Boston

07962

Local Institution - 0188, Morristown

T6G 1Z2

Local Institution - 0140, Edmonton

V5Z 4E6

Local Institution - 0165, Vancouver

N6A 4L6

Local Institution - 0141, London

K1H 8L6

Local Institution - 0143, Ottawa

M5G 2M9

Local Institution - 0166, Toronto

H2X 3E4

Local Institution - 0139, Montreal

G1J 1Z4

Local Institution - 0142, Québec

656 53

Local Institution - 0092, Brno

500 05

Local Institution - 0091, Hradec Králové

128 08

Local Institution - 0090, Prague

180 81

Local Institution - 0167, Prague

00290

Local Institution - 0071, Helsinki

04103

Local Institution - 0178, Leipzig

Unknown

Local Institution - 0035, Dublin

Local Institution - 0034, Dublin

T12DFK4

Local Institution - 0033, Cork

01

Local Institution - 0168, Dublin

Padova

Local Institution - 0118, Padua

00144

Local Institution - 0177, Roma

1066 CX

Local Institution - 0010, Amsterdam

2333 ZA

Local Institution - 0012, Leiden

6525 GC

Local Institution - 0013, Nijmegen

0424

Local Institution - 0123, Oslo

80-952

Local Institution - 0109, Gdansk

31-115

Local Institution - 0133, Krakow

93-513

Local Institution - 0060, Lodz

02-781

Local Institution - 0059, Warsaw

08916

Local Institution - 0152, Badalona-Barcelona

08035

Local Institution - 0151, Barcelona

08036

Local Institution - 0175, Barcelona

413 45

Local Institution - 0182, Gothenberg

171 76

Local Institution - 0184, Stockholm

G12 0YN

Local Institution - 0039, Glasgow

SW3 6JJ

Local Institution - 0038, London

M20 4XB

Local Institution - 0119, Manchester

HA6 2JR

Local Institution - 0041, Northwood

NG5 1PB

Local Institution - 0122, Nottingham

CB2 2QQ

Local Institution - 0037, Cambridge

SA2 8QA

Local Institution - 0040, Swansea

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY