Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

April 30, 2014

Study Completion Date

April 30, 2014

Conditions
Hepatitis C
Interventions
DRUG

Ribavirin

weight-based doses (1000 mg/day administered BID \[twice daily\] for subjects ≤ 75 kg and 1200 mg/day administered BID for subjects \> 75 kg). Those subjects receiving 1000 mg/day RBV will take 2 tablets of 200 mg/tablet in the morning and 3 tablets in the evening, and those subjects receiving 1200 mg/day RBV will take 3 tablets morning and evening.

DRUG

Hydroxychloroquine

subjects will receive HCQ 575 mg administered as a single tablet once daily (QD)

Trial Locations (2)

Unknown

Hospital St. Joseph, Marseille

Cochin Hospital, Paris

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BioLineRx, Ltd.

INDUSTRY

NCT01833845 - Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C | Biotech Hunter | Biotech Hunter