Small Molecules, Biologics
Total Trials
25
As Lead Sponsor
18
As Collaborator
7
Total Enrollment
2,170
NCT00374881
A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects
Phase: Phase 1/2
Role: Lead Sponsor
Start: Sep 30, 2006
Completion: Aug 31, 2007
NCT00480246
A Positron Emission Tomography (PET) Study to Assess the Degree of Dopamine-2 (D2) Receptor Occupancy in the Human Brain After Single Doses of BL-1020 or Perphenazine in Healthy Male Subjects Using [11C]Raclopride as PET Tracer
Phase: Phase 1
Start: May 31, 2007
Completion: Not specified
NCT00480571
Safety and Tolerability of BL-1020 in Hospitalized Subjects With Chronic Schizophrenia or Schizo-Affective Disorder
Phase: Phase 2
Start: Jun 30, 2007
Completion: Dec 31, 2007
NCT00557531
Safety and Feasibility of the Injectable BL-1040 Implant
Start: Mar 31, 2008
Completion: Jan 31, 2014
NCT00722176
Extension Study To Evaluate The Long-Term Safety, Tolerability, And Efficacy Of Low And High Doses Of Bl-1020
Start: Jun 30, 2008
Completion: Dec 31, 2009
NCT00567710
A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study
Start: Jul 31, 2008
Completion: Sep 30, 2009
NCT01363349
Phase IIb-III Study of BL-1020 Small Molecule for Schizophrenia
Phase: Phase 2/3
Start: May 31, 2011
Completion: Apr 30, 2013
NCT01121380
A Study Intended to Evaluate Safety, Tolerability and Pharmacokinetics (PK) Parameters of BL-1021
Start: Jun 30, 2011
Completion: Oct 31, 2011
NCT01506362
Efficacy, Pharmacodynamics, Safety and Tolerability of Oral BL-7040 in Patients With Moderately Active Ulcerative Colitis
Start: Mar 31, 2012
Completion: May 31, 2013
NCT01833845
Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C
Start: Apr 30, 2013
Completion: Apr 30, 2014
NCT01838395
Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients
Completion: Jul 20, 2023
NCT01990885
Safety and Systemic Exposure Study of BL-7010 in Well-Controlled Celiac Patients.
Start: Dec 31, 2013
Completion: Oct 31, 2014
NCT02073019
A Phase I Study Evaluating Safety, Tolerability, PK and PD of BL-8040 for Stem Cell Mobilization in Healthy Volunteers
Start: Aug 31, 2014
Completion: Jul 31, 2015
NCT02502968
BL-8040 Addition to Consolidation Therapy in AML Patients
Role: Collaborator
Start: Sep 30, 2015
NCT02462252
Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome
Start: Oct 31, 2015
Completion: Nov 30, 2020
NCT02639559
Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies
Start: Mar 31, 2016
Completion: Apr 7, 2023
NCT02826486
Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients
Start: Sep 30, 2016
Completion: Sep 6, 2022
NCT03281369
A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)
Start: Oct 13, 2017
Completion: Nov 30, 2025
NCT03154827
Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)
Start: Jan 8, 2018
Completion: Apr 1, 2020
NCT03246529
A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)
Phase: Phase 3
Start: Mar 23, 2018
Completion: Sep 30, 2029
NCT04543071
Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma
Start: Nov 9, 2020
Completion: Aug 31, 2028
NCT05293171
Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects
Start: Jun 11, 2021
Completion: Aug 15, 2022
NCT05618301
Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)
Start: Jul 7, 2023
Completion: Jun 24, 2025
NCT06547112
A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization
Start: Oct 31, 2024
Completion: Aug 19, 2025
NCT06442761
SCD Stem Cell Mobilization and Apheresis Using Motixafortide
Start: Nov 14, 2024
Completion: Jul 31, 2028
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