435
Participants
Start Date
June 30, 2013
Primary Completion Date
April 30, 2015
Study Completion Date
April 30, 2015
MVA Smallpox Vaccine
Subjects receive two dose regimen of IMVAMUNE® (1x10\^8 TCID50/0.5 mL per dose) via the SC route using either a syringe and needle or the Stratis™ system. Arm A receives doses via syringe and needle on days 1 and 29; Arm B receives doses via syringe and needle on days 1 and 15, Arm C receives doses via syringe and needle on days 1 and 22, Arm D receives doses via Stratis on days 1 and 29.
Emory Vaccine Center - The Hope Clinic, Decatur
University of Iowa - Vaccine Research and Education Unit, Iowa City
University of Maryland Medical System - General Clinical Research Center (GCRC), Baltimore
Saint Louis University - Center for Vaccine Development, St Louis
Baylor College of Medicine - Molecular Virology and Microbiology, Houston
Group Health Research Institute - Seattle - Vaccines and Infectious Diseases, Seattle
National Institute of Allergy and Infectious Diseases (NIAID)
NIH