Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III

PHASE3CompletedINTERVENTIONAL
Enrollment

499

Participants

Timeline

Start Date

December 30, 2013

Primary Completion Date

September 30, 2018

Study Completion Date

September 30, 2018

Conditions
Intracerebral Hemorrhage
Interventions
DRUG

rt-PA

Up to 9 doses of 1.0 mg of rt-PA will be administered through the catheter that was placed directly into the intracerebral hemorrhage using minimally invasive surgery.

Trial Locations (84)

2015

Royal Prince Alfred Hospital, Camperdown

3050

Royal Melbourne Hospital, Parkville

4032

University of Debrecen, Debrecen

5006

Royal Adelaide Hospital, North Adelaide

6720

University of Szeged, Szeged

7623

University of Pecs, Pécs

10029

Mount Sinai Medical Center, New York

10065

Weill Cornell Medical College, New York

10467

Albert Einstein College of Medicine - Montefiore Medical Center, The Bronx

11030

North Shore Long Island Jewish Health System, Manhasset

13210

State University of New York, Upstate Medical University, Syracuse

14203

University of Buffalo, Buffalo

15213

University of Pittsburgh Medical Center, Pittsburgh

19001

Abington Memorial Hospital, Abington

19107

Thomas Jefferson University Hospital, Philadelphia

19140

Temple University School of Medicine, Philadelphia

21201

University of Maryland, Baltimore

21287

Johns Hopkins University, Baltimore

22042

Fairfax INOVA Hospital, Falls Church

22908

University of Virginia Medical Center, Charlottesville

23298

Virginia Commonwealth University, Richmond

27157

Wake Forest University Baptist Medical Center, Winston-Salem

27710

Duke University Medical Center, Durham

29425

Medical University of South Carolina, Charleston

30046

Gwinnett Medical Center, Lawrenceville

32224

Mayo Clinic, Jacksonville, Jacksonville

35294

University of Alabama at Birmingham, Birmingham

37232

Vanderbilt University Medical Center, Nashville

40202

University of Louisville, Louisville

45219

University of Cincinnati Medical Center, Cincinnati

45409

Miami Valley Hospital, Dayton

47012

Hospital Universitario Rio Hortega, Valladolid

48190

University of Michigan, Ann Arbor

48202

Henry Ford Heath System, Detroit

48903

Hospital Universitario Cruces, Barakaldo

52621

The Chaim Sheba Medical Center at Tel Hashomer, Tel Litwinsky

53127

University of Bonn, Bonn

53792

University of Wisconsin, Madison

55415

Hennepin County Medical Center, Minneapolis

60201

Northshore University Health System, Evanston, Evanston

60305

Loyola University Chicago, Maywood

60611

Northwestern University, Chicago

60612

Rush University, Chicago

University of Illinois at Chicago, Chicago

60637

University of Chicago Medical Center, Chicago

63110

Washington University, St Louis

64111

St. Luke's Hospital of Kansas City, Kansas City

66160

University of Kansas Medical Center, Kansas City

69120

University of Heidelberg, Heidelberg

75390

University of Texas Southwestern at Dallas, Dallas

77030

University of Texas, Houston, Houston

78229

University of Texas at San Antonio, San Antonio

81925

University of Munich, Munich

84107

Intermountain Neurosciences Institute, Murray

84132

University of Utah, Salt Lake City

85006

Banner Good Samaritan Hospital, Phoenix

85013

Barrow Neurological Institute, Phoenix

87131

University of New Mexico, Albuquerque

90095

University of California, Los Angeles, Los Angeles

92037

Scripps Health, La Jolla

92103

University of California, San Diego, San Diego

94305

Stanford University, Stanford

95608

Mercy San Juan Medical Center, Carmichael

97225

Providence Brain and Spine Institute, Portland

100700

Bayi Brain Hospital, Beijing Military General Hospital, Beijing

400038

Southwest Hospital, Third Military Medical University, Chongqing

510180

Guangzhou First People's Hospital, Guangzhou

06102

Hartford Hospital, Hartford

06510

Yale University, New Haven

04102

Maine Medical Center, Portland

08901

Rutgers - Robert Wood Johnson Medical School, New Brunswick

T6G 2B7

University of Alberta, Edmonton

L8L 2X2

McMaster University, Hamilton

H3A 2B4

Montreal Neurological Institute, McGill University, Montreal

D-55131

University of Mainz, Mainz

Unknown

Rabin Medical Center, Petah Tikva

Hospital Universitario Mutua de Terrassa, Barcelona

Newcastle Royal Victoria Infirmary, Newcastle upon Tyne

08035

Vall d'Hebron University Hospital, Barcelona

08041

Hospital de la Santa Creu i Sant Pau, Barcelona

08907

Bellvitge, Barcelona

M6 8HD

Salford Royal NHS Foundation Trust, Salford

G51 4TF

South Glasgow University Hospital, Glasgow

SO16 6YD

University of Southampton Hospital, Southampton

All Listed Sponsors
lead

Johns Hopkins University

OTHER

collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Genentech, Inc.

INDUSTRY

collaborator

Emissary International LLC

INDUSTRY