A Validation of a Genomics Based Prognostic in Severe Trauma

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 31, 2013

Primary Completion Date

November 30, 2016

Study Completion Date

July 23, 2019

Conditions
Trauma; ComplicationsMultiple Organ Failure
Interventions
OTHER

Traumatized population

In the traumatized population (severe blunt traumatic injury), blood samples will be collected at admission, days 1, 4, 7, 14, 21 and 28, or until discharge from the ICU or death. A total of 5 mLs of blood will be collected at admission and day 1, 4 mLs of blood will be collected at each remaining time point.

OTHER

Healthy Volunteers

The healthy volunteer participants will donate a one-time 5 mL blood sample which will undergo rapid leukocyte genomic screening. These controls will allow the investigators to determine if the values obtained are accurate, reliable, and repeatable.

Trial Locations (2)

32610

UF Laboratory of Inflammation Biology and Surgical Science and Shands Hospital at UF, Gainesville

98104

UW Harborview Research and Training Building, Seattle

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

collaborator

Massachusetts General Hospital

OTHER

lead

University of Florida

OTHER

NCT01810328 - A Validation of a Genomics Based Prognostic in Severe Trauma | Biotech Hunter | Biotech Hunter