FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir

PHASE4CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

April 25, 2013

Primary Completion Date

February 19, 2016

Study Completion Date

February 7, 2017

Conditions
HIV-1 Infection
Interventions
DRUG

Emtricitabine/rilpivirine/tenofovir disoproxil fumarate

"Step 1: From entry through week 12, the participants received no study treatment. From week 12 through week 60, the participants received one fixed dose combination emtricitabine/rilpivirine/tenofovir disoproxil fumarate (FTC/RPV/TDF) tablet daily.~Step 2 (Optional): From week 60 through week 108, the participants either received one FTC/RPV/TDF tablet daily or no study treatment."

Trial Locations (19)

10457

Bronx-Lebanon Hosp. Ctr. CRS (31469), The Bronx

14642

University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787), Rochester

15213

Pitt CRS (1001), Pittsburgh

19104

Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia

20009

Whitman Walker Health CRS (31791), Washington D.C.

21201

IHV Baltimore Treatment CRS (4651), Baltimore

27401

Moses H. Cone Memorial Hospital CRS (3203), Greensboro

27516

Unc Aids Crs (3201), Chapel Hill

30308

The Ponce de Leon Ctr. CRS (5802), Atlanta

35294

31788 Alabama CRS, Birmingham

44109

Metro Health CRS (2503), Cleveland

45267

University of Cincinnati CRS (2401), Cincinnati

60611

Northwestern University CRS (2701), Chicago

60612

Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago

77030

Houston AIDS Research Team CRS (31473), Houston

94110

801 University of California, San Francisco HIV/AIDS CRS, San Francisco

02114

Massachusetts General Hospital ACTG CRS (101), Boston

02115

Brigham and Women's Hosp. ACTG CRS (107), Boston

02906

The Miriam Hosp. ACTG CRS (2951), Providence

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

NETWORK

NCT01777997 - FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir | Biotech Hunter | Biotech Hunter