A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of Vismodegib

PHASE1CompletedINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

February 28, 2013

Primary Completion Date

May 31, 2013

Study Completion Date

May 31, 2013

Conditions
Healthy Volunteer
Interventions
DRUG

fluconazole

Multiple oral doses

DRUG

itraconazole

Multiple oral doses

DRUG

rabeprazole

Multiple oral doses

DRUG

vismodegib

Multiple oral doses

Trial Locations (2)

32117

Daytona Beach

75247

Dallas

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY