2,000
Participants
Start Date
May 25, 2006
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Nitroglycerin 0.25 mg (single dose, no longer given since January 2017)
From the beginning of the study until the end of year 2016 a single dose of sublingual nitroglycerin was given to examine the associated acute haemodynamic effects (recordings completed).
Salbutamol 400 µg (single dose, no longer given since January 2017)
From the beginning of the study until the end of year 2016 a 400 µg dose of inhaled salbutamol was given to examine the associated acute haemodynamic effects (recordings completed).
L-arginine (10 min infusion, no longer given since January 2017)
From the beginning of the study until the end of year 2016 L-arginine infusion 10 mg/kg/min could be given for 10 minutes to examine acute haemodynamic effects (recordings completed).
Liquorice (2 weeks, glycyrrhizin 290-370 mg daily, no longer given since 2012)
Daily liquorice intake (daily glycyrrhizin dose 290-370 mg) for two weeks, measurements before and after intervention (recordings completed).
Small milk casein-derived polypeptides (12 weeks daily, recordings completed 2011)
Daily intake of yoghurt containing small milk casein-derived polypeptides (12 weeks) and placebo yoghurt (12 weeks), measurements before and after intervention (recordings completed 2011).
Bisoprolol (5 mg daily for 3 weeks, recordings completed 2011)
Bisoprolol 5 mg daily for 3 weeks and placebo tablet daily for 3 weeks, double-blind, randomized, placebo-controlled cross-over protocol. Measurements before and after interventions (recordings completed 2011).
RECRUITING
Tampere University, Tampere
RECRUITING
Tampere University Hospital, Tampere
Collaborators (1)
Finnish Foundation for Cardiovascular Research
OTHER
Paavo Nurmi Foundation
UNKNOWN
Sigrid Jusélius Foundation
OTHER
Finnish Cultural Foundation
OTHER
Tampere Tuberculosis Foundation
OTHER
Medical Research Fund of the Tampere University Hospital, Finland
OTHER
Aarne Koskelo Foundation
OTHER
Finnish Medical Foundation
NETWORK
Finnish Kidney Foundation
UNKNOWN
Päivikki and Sakari Sohlberg Foundation, Finland
OTHER
Tampere University
OTHER