NCT01719978View on ClinicalTrials.gov

Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics

PHASE4CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

October 31, 2007

Study Completion Date

December 31, 2011

Conditions
Cardiac Arrhythmias
Interventions
DRUG

3.6mL 2% Mepivacaine with 1:100,000 epinephrine

Local anesthetic with vasoconstrictor

PROCEDURE

Lower Third Molar Extraction

Lower Third Molar Extraction with LA + hyaluronidase (or placebo)

DRUG

Hyaluronidase

75RTU Hyaluronidase administration concomitant to the local anesthetic

DRUG

Placebo

1mL 0.9% saline administration concomitant to the local anesthetic

Trial Locations (1)

05508-000

Stomatology Department, FOUSP, São Paulo

All Listed Sponsors
collaborator

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

OTHER_GOV

lead

Mauricio Jose Tornelli

OTHER

NCT01719978 - Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics | Biotech Hunter | Biotech Hunter