Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

November 23, 2012

Primary Completion Date

October 31, 2015

Study Completion Date

February 12, 2019

Conditions
Colorectal Cancer
Interventions
DRUG

LGX818

DRUG

Cetuximab

DRUG

BYL719

Trial Locations (52)

3000

UZ Gasthuisberg, Leuven

3050

Royal Melbourne Hospital, Parkville

10022

Memorial Sloan Kettering Cancer Center, New York

28026

Hospital Universitario 12 de Octubre, Madrid

31052

EDOG - Institut Claudius Regaud - PPDS, Toulouse

34298

Centre Régional de Lutte Contre Le Cancer Val D'aurelle Paul Lamarque, Montpellier

37055

Tennessee Oncology, PLLC, Dickson

37066

Tennessee Oncology, PLLC, Gallatin

37067

Tennessee Oncology, PLLC, Franklin

37076

Tennessee Oncology, PLLC, Hermitage

37129

Tennessee Oncology, PLLC, Murfreesboro

37160

Tennessee Oncology, PLLC, Shelbyville

37167

Tennessee Oncology, PLLC, Smyrna

37203

Tennessee Oncology, PLLC, Nashville

37205

Tennessee Oncology, PLLC, Nashville

37207

Tennessee Oncology, PLLC, Nashville

37211

Tennessee Oncology, PLLC, Nashville

37909

Tennessee Oncology, PLLC, Lebanon

41013

Hospital Universitario Virgen del Rocio - PPDS, Seville

41100

Ospedaliero Universitaria di Modena Policlinico, Modena

45147

Universitätsklinikum Essen, Essen

50937

University Hospital of Koln, Cologne

84112

Huntsman Cancer Hospital, Salt Lake City

84119

Redwood Health Center - ARUP Lab Draw Location, Salt Lake City

84132

John A Moran Eye Center, Salt Lake City

90033

Keck Hospital of USC, Los Angeles

LAC&USC Medical Center, Los Angeles

USC/Norris Comprehensive Cancer Center, Los Angeles

90095

Ronald Reagan UCLA Medical Center, Los Angeles

UCLA University of California Los Angeles, Los Angeles

Westwood Bowyer Clinic, Peter Morton Medical Building, Los Angeles

90404

UCLA Hematology Oncology, Santa Monica

UCLA Santa Monica Medical Center & Orthopaedic Hospital, Santa Monica

06510

Smilow Cancer Hospital at Yale-New Haven, New Haven

06520

Yale University, New Haven

06473

Smilow Cancer Hospital Care Center at North Haven, North Haven

02114-2620

Massachusetts General Hospital, Boston

07601

Hackensack University Medical Center, Hackensack

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack

10017-6706

Memorial Sloan-Kettering Cancer Center, New York

84112-5550

University of Utah - Huntsman Cancer Institute - PPDS, Salt Lake City

M5G 2M9

Princess Margaret Cancer Centre, Toronto

H3T 1E2

Sir Mortimer B. Davis Jewish General Hospital, Montreal

277-8577

Pharmacy of National Cancer Center Hospital East, Kashiwa

104-0045

National Cancer Center Hospital, Chuo-ku

1066 CX

Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam

3015 CE

Erasmus MC, Rotterdam

3584 CX

Universitair Medisch Centrum Utrecht, Utrecht

0379

Oslo Myeloma Center - PPDS, Oslo

06351

Samsung Medical Center - PPDS, Gangnam-Gu

05505

Asan Medical Center - PPDS, Songpa-Gu

08035

Instituto de Investigacion Oncologica Vall d'Hebron (VHIO) - EPON, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT01719380 - Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer | Biotech Hunter | Biotech Hunter