Effect of Broccoli Sprouts Homogenate on SS RBC

NACompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

March 31, 2012

Primary Completion Date

April 30, 2015

Study Completion Date

April 30, 2015

Conditions
Sickle Red Blood CellFetal HemoglobinOxidative Stress
Interventions
DIETARY_SUPPLEMENT

Broccosprouts® (Brassica Protection Products LLC) homogenate

"In the in-vitro part of the study, sulphoraphane will be added into the culture media used to grow and differentiate the erythroid cells from blood samples obtained from three Hb AA volunteers and three Hb SS subjects. The subjects will have a single clinic visit for the blood donation.~In the second part of the study, enrolled subjects will be asked to consume homogenates of broccoli sprouts by mouth daily for three weeks. They will have a maximum of five clinic visits for medical assessments and lab draws during this time. They will then have a final clinic visit after a washout period of six weeks."

Trial Locations (1)

27710

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Doris Duke Charitable Foundation

OTHER

lead

Duke University

OTHER