Study Evaluating TheSafety And Efficacy Of PF-05212377 Or Placebo In Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms On Donepezil

PHASE2TerminatedINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

November 30, 2012

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Alzheimer's Disease
Interventions
DRUG

PF-05212377 (SAM-760)

30 mg QD of PF-05212377 (SAM-760)

OTHER

Placebo

Placebo QD

Trial Locations (60)

1217

Covance Laboratories, Switzerland

10021

Eastside Comprehensive Medical Center, LLC, New York

10245

Dr. med. Volker Schumann, Arzt fuer Nervenheilkunde, Berlin

10305

Behavioral Medical Research of Staten Island, Staten Island

10365

Praxis Dr. Franz- Arztehaus am KEH mit Epilepsie-Zentrum, Berlin

13156

Praxis Dr. sc. med. Alexander Schulze, Berlin

14642

University of Rochester Medical Center (MRI Imaging Only), Rochester

19403

Keystone Clinical Studies, LLC, Norristown

28049

Hospital de Cantoblanco, Madrid

29401

Roper Hospital (Imaging Only), Charleston

Roper St. Francis Healthcare, Charleston

Roper St. Francis Pharmacy (IP Shipment/Storage), Charleston

30005

Institute for Advanced Medical Research, Alpharetta

30331

Atlanta Center for Medical Research, Atlanta

31904

Columbus Research & Wellness Institute, Inc., Columbus

32763

Medical Research Group of Central Florida, Orange City

33009

MD Clinical, Hallandale

33064

Quantum Laboratories, Deerfield Beach

33407

Premiere Research Institute, West Palm Beach

33437

Diagnostic Centers of America, Boynton Beach

33445

Brain Matters Research Inc, Delray Beach

34601

Meridien Research, Brooksville

34748

Compass Research LLC-North Clinic, Leesburg

38018

Neurology Clinic, P.C., Cordova

43212

The Ohio State University (administrative offices only), Columbus

43221

The Ohio State University - 2050, Columbus

48824

Michigan State University, East Lansing

53188

Cary J. Kohlenberg, MD, dba, IPC Research, Waukesha

53226

Merrill Hills Manor, Waukesha

53562

Dean Foundation for Health, Research and Education, Middleton

63141

Metro Imaging (Imaging only), Creve Coeur

Millennium Psychiatric Associates, LLC, Creve Coeur

70629

Lake Charles Clinical Trials, Lake Charles

76309

Grayline Clinical Drug Trials, Wichita Falls

78757

Senior Adults Speciality Research Inc., Austin

83500

Espace Sante 2, La Seyne-sur-Mer

90402

Praxis fuer Neurologie / Psychiatrie Prof. Dr. Steinwachs, Nuremberg

92251

Sun Valley Research Center, Imperial

92270

Desert Valley Research, Rancho Mirage

92626

ATP Clinical Research, Inc, Costa Mesa

92705

RAA - Apex Aquisition, LLC, Santa Ana

1270244

Psicomed Estudios Medicos CIA. LTDA, Antofagasta

7500710

Biomedica Research Group, Santiago

7560356

Especialidades Medicas L Y S, Santiago

06518

Geriatric and Adult Psychiatry LLC, Hamden

06510

Yale University, New Haven

Yale-New Haven Hospital, Temple Radiology, New Haven

06520

Yale University School of Medicine, MRI Research Center (MRI), New Haven

New York

"University of Rochester Medical Center AD-CARE Program , University of Rochester Medical Center"

05201

Clinical Neuroscience Research Assoc. d/b/a The Memory Clinic, Bennington

B3S 1M7

True North Clinical Research Halifax, Inc., Halifax

N7L 1C1

Chatham-kent Clinical Trials Research Centre, Chatham

N7M 5L9

Chatham-Kent Clinical Trials Research Centre, Chatham

J8T 8J1

Recherches Neuro-Hippocampe Inc., Gatineau

04107

Arzneimittelforschung Leipzig Gmbh, Leipzig

03203

Hospital General Universitario De Elche, Elche

BA1 3NG

The Research Institute for the Care of Older People Centre, Bath

CB21 5EF

Fulbourn Hospital, Cambridge

KT16 0AE

Surrey and Borders Partnership NHS Foundation Trust, Chertsey

NN5 6UD

Berrywood Hospital, Northampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY