183
Participants
Start Date
August 31, 2012
Primary Completion Date
October 31, 2016
Study Completion Date
October 31, 2016
Tcelna
Autologous pool of myelin reactive T-cells (MRTC) expanded ex vivo with immunodominant epitopes selected from the three myelin antigens, MBP, PLP and MOG on a per subject basis. Attenuated by irradiation to prevent further proliferation before releasing product for administration.
Placebo
2 ml of Tcelna excipients, prepared daily as individual doses and irradiated before releasing product for administration.
Island Neurological Assoicates, PC, Plainview
University of Pennsylvania, Philadelphia
Neurological Associates, Inc, Richmond
Hampton Roads Neurology, Newport News
The Neurological Institute, PA, Charlotte
Carolinas Medical Center Neurology, Charlotte
PMG Research of Charlotte, Charlotte
Shepherd Center, Atlanta
Neurology Associates, P.A., Maitland
Neurological Services of Orlando, Orlando
Vero Beach Neurology, Vero Beach
University of Miami, Miami
Meridien Research, Tampa
Collier Neurologic Specialists, LLC, Naples
Associates in Neurology, Lexington
Neurology Specialists, Inc, Dayton
Josephson Wallack Munshower Neurology, PC, Indianapolis
Fort Wayne Neurological Center, Fort Wayne
Consultants In Neurology, Ltd., Northbrook
University of Kansas Medical Center, Kansas City
The Maxine Mesinger MS Clinic/Baylor College of Medicine, Houston
Integra Clinical Research, LLC, San Antonio
Central Texas Neurology, Round Rock
HOPE Research Institute, Phoenix
Northwest NeuroSpecialists, LLC, Tucson
Alta Bates Summit Medical Center, The Research and Education Development Institute, Berkeley
Providence St. Vincent Medical Center - Northwest MS Center, Portland
Providence Medical Group - Medford, Medford
Swedish Neuroscience Institute, Issaquah
Swedish Neuroscience Institute, Seattle
Saint Elizabeth's Medical Center, Boston
University Hospital and Medical Center Stony Brook New York, Stony Brook
Fletcher Allen Health Care - Neurology Service, Burlington
University of Ottawa, Ottawa
Recherche Sepmus Inc., Greenfield Park
Montreal Neurological Institute and Hospital, Montreal
Lead Sponsor
Opexa Therapeutics, Inc.
INDUSTRY