An Extension Study of RO5045337 in Participants Participating in Previous Roche-sponsored Cancer Studies

PHASE1CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

November 28, 2012

Primary Completion Date

June 26, 2017

Study Completion Date

June 26, 2017

Conditions
Myelogenous Leukemia, Chronic, Neoplasms, Myelogenous Leukemia, Acute
Interventions
DRUG

RO5045337

Participants will receive RO5045337 orally in doses ranging from 20 milligram per square meter (mg/m\^2) to 1800 mg/m\^2 daily, and up to 1500 mg dose twice daily on a variety of schedules including daily for up to 20 days and weekly dosing for 3 weeks in 28 day cycles until disease progression or unacceptable toxicity with maximum treatment duration of 24 months.

Trial Locations (5)

31059

Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse

77030

M.D Anderson Cancer Center; Oncology, Houston

78229

Cancer Therapy & Research Ctr; Dept Institute for Drug Development, San Antonio

90403

Sarcoma Oncology Center, Santa Monica

M5G 2M9

Princess Margaret Hospital, Medical Oncology & Haematology, Toronto

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT01677780 - An Extension Study of RO5045337 in Participants Participating in Previous Roche-sponsored Cancer Studies | Biotech Hunter | Biotech Hunter