11
Participants
Start Date
November 28, 2012
Primary Completion Date
June 26, 2017
Study Completion Date
June 26, 2017
RO5045337
Participants will receive RO5045337 orally in doses ranging from 20 milligram per square meter (mg/m\^2) to 1800 mg/m\^2 daily, and up to 1500 mg dose twice daily on a variety of schedules including daily for up to 20 days and weekly dosing for 3 weeks in 28 day cycles until disease progression or unacceptable toxicity with maximum treatment duration of 24 months.
Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse
M.D Anderson Cancer Center; Oncology, Houston
Cancer Therapy & Research Ctr; Dept Institute for Drug Development, San Antonio
Sarcoma Oncology Center, Santa Monica
Princess Margaret Hospital, Medical Oncology & Haematology, Toronto
Hoffmann-La Roche
INDUSTRY