A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD)

PHASE2CompletedINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

December 31, 2012

Primary Completion Date

April 30, 2015

Study Completion Date

April 30, 2015

Conditions
Obsessive-Compulsive Disorder
Interventions
DRUG

Bitopertin

Bitopertin once daily orally.

DRUG

Placebo

Placebo matched to bitopertin once daily orally.

DRUG

SSRI

Participants will continue their background SSRI treatment as per standard of care at the same dose taken during the 8 weeks prior to Day 1. Protocol does not enforce any particular SSRI drug or regimen.

Trial Locations (34)

3273

Medical Research Group of Central Florida, Orange City

10029

Mount Sinai School of Medicine; Department of Psychiatry, New York

10128

Medical Research Network - New York, New York

14618

Finger Lakes Clinical Research, Rochester

19403

Keystone Clinical Studies, LLC, Norristown

30030

iResearch Atlanta, Decatur

30080

Carman Research, Smyrna

33701

University of South Florida, St. Petersburg

34748

Compass Research North, LLC, Leesburg

38119

Clinical Neuroscience Solutions,Inc, Memphis

39232

Precise Research Centers, Flowood

44130

North Star Research, Middleburg Heights

53562

Dean Foundation, Middleton

55454

Ambulatory Research Center (ARC), Department of Psychiatry, Minneapolis

60637

Uni of Chicago; Centre For Advanced Medicine, Chicago

63141

St Louis Clinical Trials, St Louis

70114

Louisiana Research Associates, New Orleans

73103

Ips Research Company, Oklahoma City

78731

FutureSearch Trials, LP, Austin

92056

Excell Research, Oceanside

94305

Stanford University School of Medicine, Stanford

98033

Eastside Therapeutic Resource, Kirkland

06519

Yale University School of Medicine; Neuroscience Research Training Program, New Haven

33613-4706

University of South Florida, Tampa

02114

Massachusetts General Hospital - East, Boston

02131

Boston Clinical Trials, Boston

02906

Butler Hospital - Department of Psychiatry and Human Behavior, Providence

T6L 6W6

Chokka Center for Integrative Health, Edmonton

V1Y 2H4

Okanagan Clinical Trials, Kelowna

B3S 1M7

True North Clinical Research-Halifax, Halifax

B4N 4K9

True North Clinical Research Kentville, Kentville

L8S 1B7

McMaster University - MacAnxiety Research Centre, Hamilton

L5M 4N4

Sunny Johnson Medical Research Associates Inc.; Medical Research Associates, Mississauga

M4W 2N4

START Clinic for Mood & Anxiety Disorders, Toronto

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT01674361 - A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD) | Biotech Hunter | Biotech Hunter