Safety and Efficacy Study of Enzalutamide Versus Bicalutamide in Men With Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

396

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

February 28, 2015

Study Completion Date

January 31, 2018

Conditions
Prostate Cancer
Interventions
DRUG

Enzalutamide

160 mg, daily, by mouth.

DRUG

Bicalutamide

50 mg, daily, by mouth

Trial Locations (109)

11530

AccuMed Research Associates, Garden City

12601

Premier Medical Group of the Hudson Valley PC, Poughkeepsie

13210

Associated Medical Professionals of NY, PLLC, Syracuse

15232

UPMC Cancer Center Hillman Cancer Center, Pittsburgh

16801

Mount Nittany Physician Group, State College

16803

Mount Nittany Health, State College

17604

Lancaster Urology, Lancaster

19107

Jefferson Medical Oncology, Philadelphia

Jefferson Urology Associates, Philadelphia

Thomas Jefferson University Hospital, Philadelphia

20037

George Washington University - Medical Faculty Associates, Washington D.C.

21204

Chesapeake Urology Research Associates, Towson

23462

Urology of Virginia, PLLC., Virginia Beach

23502

Virginia Oncology Associates, Norfolk

23666

Virginia Oncology Associates, Hampton

27103

Wake Forest Baptist Health Urology, Winston-Salem

27157

Wake Forest Baptist Health, Winston-Salem

27403

Alliance Urology Specialists, PA, Greensboro

27710

Duke University Medical Center, Durham

Investigational Chemotherapy Services, Durham

28025

Carolina Clinical Trials, LLC, Concord

Carolina Urology Partners, PLLC, Concord

28144

Rowan Regional Medical Center, Salisbury

28278

Carolinas Medical Center-Steelcreek, Charlotte

29414

Charleston Hematology Oncology Associates, PA, Charleston

29572

Carolina Urologic Research Center, Myrtle Beach

32114

Advanced Urology institute, Daytona Beach

32207

East Coast Institute for Research, LLC, Jacksonville

32216

East Coast Institute for Research, LLC, Jacksonville

34102

Specialists In Urology, Naples

35233

University of Alabama at Birmingham, Birmingham

35249

University of Alabama at Birmingham,IDS Pharmacy, Birmingham

35294

University of Alabama at Birmingham, Birmingham

37209

Urology Associates P.C., Nashville

37232

Vanderbilt University Medical Center, Nashville

44195

Cleveland Clinic Taussig Cancer Institute, Cleveland

45212

TriState Urologic Services PSC Inc., dba The Urology Group, Cincinnati

47130

First Urology, PSC, Jeffersonville

48084

Michigan Institute of Urology, Troy

53792

University of Wisconsin Clinical Sciences Center, Madison

55125

Minnesota Oncology Hematology, P.A., Woodbury

63110

Barnes-Jewish Hospital, St Louis

Washington University Infusion Center Pharmacy, St Louis

Washington University, School of Medicine, 7th Floor, Center for Advanced Medicine, St Louis

63129

Siteman Cancer Center - South County, St Louis

63141

Barnes-Jewish West County Hospital, Creve Coeur

68130

GU Research network,LLC / Urology Cancer Center, Omaha

70006

Metairie Oncologist, LLC, Metairie

70121

Ochsner Clinic Foundation, New Orleans

71106

Regional Urology, LLC, Shreveport

75231

Urology Clinics of North Texas, Dallas

75246

Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas

77024

Texas Oncology-Memorial City, Houston

78229

Urology San Antonio Research, San Antonio

80045

Anschutz Cancer Center Pavilion Pharmacy, Aurora

Anschutz Inpatient Pavilion, Aurora

University of Colorado Cancer Center, Anschutz Cancer Pavilion, Aurora

80211

The Urology Center of Colorado, Denver

84112

University of Utah/Huntsman Cancer Hospital, Salt Lake City

University of Utah/Huntsman Cancer Institute, Salt Lake City

85255

Desert Springs Cancer Care, Scottsdale

85704

Arizona Oncology Associates, PC - HOPE, Tucson

85710

Arizona Oncology Associates, PC - HOPE, Tucson

85715

Urological Associates of Southern Arizona, PC, Tucson

85741

Urological Associates of Southern Arizona, PC, Tucson

90027

Southern California Permanente Medical Group, Los Angeles

90048

Tower Urology, Los Angeles

90095

UCLA Clark Urology Clinic, Los Angeles

UCLA Department of Pharmaceutical Services, Los Angeles

90505

Skyline Urology, Torrance

91411

Skyline Urology, Sherman Oaks

92078

Southern California Permanente Medical Group, San Marcos

92120

Southern California Permanente Medical Group, San Diego

92404

San Bernardino Urological Associates Medical Group, San Bernardino

92806

Southern California Permanente Medical Group, Anaheim

94041

Kaiser Permanente Medical Center Lab Drawing Station, Moutain View

94063

Kaiser Permanente Medical Center Lab Drawing Station, Redwood City

94080

Kaiser Permanente Medical Center, South San Francisco

94115

Kaiser Permanente Medical Center, San Francisco

94305

Standford Health Care, Stanford

94509

Kaiser Permanente Medical Center Lab Drawing Station, Antioch

94531

Kaiser Permanente Medical Center Lab Drawing Station, Antioch

94553

Kaiser Permanente Medical Center Lab Drawing Station, Martinez

94558

Kaiser Permanente Medical Center Lab Drawing Station, Pleasanton

94577

Kaiser Permanente Medical Center, San Leandro

94589

Kaiser Permanente Medical Center, Vallejo

94596

Kaiser Permanente Medical Center, Walnut Creek

94611

Kaiser Permanente Medical Center, Oakland

95020

Kaiser Permanente Medical Center Lab Drawing Station, Gilroy

95051

Kaiser Permanente Medical Center, Santa Clara

95119

Kaiser Permanente Medical Center, San Jose

95356

Kaiser Permanente Medical Center Lab Drawing Station, Modesto

95661

Kaiser Permanente Medical Center, Roseville

95817

UC Davis Comprehensive Cancer Center, Sacramento

UC Davis Medical Center, Sacramento

95825

Kaiser Permanente Medical Center, Sacramento

97301

Salem Hospital, Salem

97439

Peace Harbor Hospital, Florence

97477

Oregon Urology Institute, Springfield

Sacred Heart Nuclear Medicine, Springfield

98101

Virginia Mason Medical Center, Seattle

98109

Seattle Cancer Care Alliance, Seattle

98195

University of Washington Medical Center, Seattle

94533-6901

Kaiser Permanente Medical Center Lab Drawing Station, Fairfield

95035-5491

Kaiser Permanente Medical Center Lab Drawing Station, Milpitas

94558-3313

Kaiser Permanente Medical Center Lab Drawing Station, Napa

55435-2150

Minnesota Oncology Hematology, P.A., Edina

07601

Hackensack University Medical Center, Hackensack

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Astellas Pharma Inc

INDUSTRY

collaborator

Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

INDUSTRY

lead

Pfizer

INDUSTRY