Using mTOR Inhibitors in the Prevention of BK Nephropathy

Reduction of standard immunosuppression - The standard of care immunosuppression treatment commonly used for renal transplant patients

Myfortic or CellCept - The standard of care immunosuppression treatment most commonly used for renal transplant patients

mTOR Substitution - Replacing tacrolimus (a calcineurin inhibitor) with sirolimus (an mTOR inhibitor) along with reduction of mycophenolic acid