NCT01643070View on ClinicalTrials.gov

Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases

PHASE2CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

September 30, 2014

Study Completion Date

December 31, 2015

Conditions
Rectal CancerLiver Metastases
Interventions
DRUG

Capecitabine, Oxaliplatin

Induction chemotherapy - Induction XELOX (Capecitabine 1250 mg/m2 PO twice daily on D1-14 and oxaliplatin 130 mg/m2 on D1, every 3 weeks for 2 cycles) Preoperative chemoradiotherapy - XELOX RT (Capecitabine 825 mg/m2 PO twice daily during radiotherapy and oxaliplatin 50 mg/m2/day on weekly.)

RADIATION

Radiotherapy

Preoperative radiotherapy, 5040 cGy with 28 fractions

Trial Locations (1)

138736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
lead

Asan Medical Center

OTHER