NCT01638533 - Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 3, 2012

Primary Completion Date

November 29, 2018

Study Completion Date

September 1, 2020

Conditions

GliomaHematopoietic and Lymphoid Cell NeoplasmLymphomaMetastatic Malignant Solid NeoplasmNeuroendocrine NeoplasmRecurrent Adult Soft Tissue SarcomaRecurrent Bladder CarcinomaRecurrent Breast CarcinomaRecurrent Chronic Lymphocytic LeukemiaRecurrent Colorectal CarcinomaRecurrent Head and Neck CarcinomaRecurrent Lung CarcinomaRecurrent Malignant Solid NeoplasmRecurrent MelanomaRecurrent Pancreatic CarcinomaRecurrent Primary Cutaneous T-Cell Non-Hodgkin LymphomaRecurrent Prostate CarcinomaRecurrent Renal Cell CarcinomaRecurrent Thyroid Gland CarcinomaRefractory Chronic Lymphocytic LeukemiaRefractory Mature T-Cell and NK-Cell Non-Hodgkin LymphomaRefractory Primary Cutaneous T-Cell Non-Hodgkin LymphomaStage III Breast Cancer AJCC v7Stage III Colorectal Cancer AJCC v7Stage III Cutaneous Melanoma AJCC v7Stage III Lung Cancer AJCC v7Stage III Pancreatic Cancer AJCC v6 and v7Stage III Prostate Cancer AJCC v7Stage III Renal Cell Cancer AJCC v7Stage III Soft Tissue Sarcoma AJCC v7Stage IIIA Breast Cancer AJCC v7Stage IIIA Colorectal Cancer AJCC v7Stage IIIA Cutaneous Melanoma AJCC v7Stage IIIB Breast Cancer AJCC v7Stage IIIB Colorectal Cancer AJCC v7Stage IIIB Cutaneous Melanoma AJCC v7Stage IIIC Breast Cancer AJCC v7Stage IIIC Colorectal Cancer AJCC v7Stage IIIC Cutaneous Melanoma AJCC v7Stage IV Breast Cancer AJCC v6 and v7Stage IV Colorectal Cancer AJCC v7Stage IV Cutaneous Melanoma AJCC v6 and v7Stage IV Lung Cancer AJCC v7Stage IV Pancreatic Cancer AJCC v6 and v7Stage IV Prostate Cancer AJCC v7Stage IV Renal Cell Cancer AJCC v7Stage IV Soft Tissue Sarcoma AJCC v7Stage IVA Colorectal Cancer AJCC v7Stage IVB Colorectal Cancer AJCC v7Unresectable Solid Neoplasm

Interventions

OTHER

Pharmacological Study

Correlative studies

DRUG

Romidepsin

Given IV

Trial Locations (12)

19107

Thomas Jefferson University Hospital, Philadelphia

20892

National Cancer Institute Developmental Therapeutics Clinic, Bethesda

21287

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore

30322

Emory University Hospital/Winship Cancer Institute, Atlanta

44106

Case Western Reserve University, Cleveland

48201

Wayne State University/Karmanos Cancer Institute, Detroit

55905

Mayo Clinic in Rochester, Rochester

60637

University of Chicago Comprehensive Cancer Center, Chicago

91010

City of Hope Comprehensive Cancer Center, Duarte

95817

University of California Davis Comprehensive Cancer Center, Sacramento

17033-0850

Penn State Milton S Hershey Medical Center, Hershey

M5G 2M9

University Health Network-Princess Margaret Hospital, Toronto