PiB PET Scanning in Speech and Language Based Dementias

PHASE1CompletedINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

March 31, 2010

Primary Completion Date

January 31, 2015

Study Completion Date

January 31, 2015

Conditions
PPAPrimary Progressive AphasiaAphasiaNon-fluent AphasiaSemantic DementiaApraxia of SpeechPrimary Progressive Nonfluent AphasiaProgressive Aphasia
Interventions
DRUG

C-11 PiB

One time intravenous administration of 740 megabecquerel (MBq) of \[N-methyl-11C\]2-(4'-methylaminophenyl)-6-hydroxybenzothiazole (PiB) (range 370 - 740 MBq).

DRUG

F-18 FDG

One time intravenous administration of 629 megabecquerel (MBq) of \[18-F\]-fluoro-deoxy-glucose (FDG) (range 555 - 740 MBq).

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER