Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea

NATerminatedINTERVENTIONAL
Enrollment

384

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

March 31, 2016

Study Completion Date

March 31, 2016

Conditions
Acute Watery DiarrheaDysentery/Febrile Diarrhea
Interventions
DRUG

Single dose rifaximin 1650 mg

Rifaximin 1650 mg as a single dose plus loperamide 4 mg initially followed by 2 mg after each unformed stool, not to exceed 16 mg/day for 2 days

DRUG

Single dose azithromycin 500 mg

Azithromycin 500 mg as a single dose plus loperamide 4 mg initially followed by 2 mg after each unformed stool, not to exceed 16 mg/day for 2 days

DRUG

Single dose levofloxacin 500 mg

Levofloxacin 500 mg as a single dose plus loperamide 4 mg initially followed by 2 mg after each unformed stool, not to exceed 16 mg/day for 2 days

DRUG

Single dose azithromycin 1000 mg plus loperamide

Azithromycin 1000 mg as a single dose plus loperamide 4 mg initially followed by 2 mg after each unformed stool, not to exceed 16 mg/day for 2 days

DRUG

Single dose azithromycin 1000 mg plus placebo

Azithromycin 1000 mg as a single dose and placebo in lieu of loperamide

Trial Locations (5)

Unknown

UK Role 3 Joint Force Hospital, Camp Bastion Air Base

U.S. Naval Expeditionary Base, Camp Lemonnier

Joint Task Force - Bravo, Soto Cano Air Base

British Army Training Unit Kenya, Nanyuki

Armed Forces Research Institute of Medical Sciences, Bangkok

All Listed Sponsors
collaborator

Navy Bureau of Medicine and Surgery

FED

collaborator

Ministry of Defence, United Kingdom

OTHER_GOV

collaborator

Naval Medical Research Center

FED

collaborator

Naval Medical Research Unit- 3

FED

collaborator

United States Army Medical Unit - Kenya

FED

collaborator

United States Naval Medical Center, Portsmouth

FED

collaborator

Naval Medical Research Unit- 6

FED

lead

Uniformed Services University of the Health Sciences

FED

NCT01618591 - Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea | Biotech Hunter | Biotech Hunter