Using Intravenous Heparin Versus Standard of Care Subcutaneous Heparin to Prevent Clots After Surgery

NACompletedINTERVENTIONAL
Enrollment

152

Participants

Timeline

Start Date

May 31, 2007

Primary Completion Date

May 31, 2014

Study Completion Date

May 31, 2014

Conditions
Venous Thrombosis
Interventions
DRUG

low dose intravenous heparin (LDIVH)

The LDIVH (experimental) group will receive a continuous heparin drip titrated to a prothrombin time (PTT) of 40-45. LDIVH subjects will have PTT tested within 24 hours prior to initiation of LDIVH. In addition, these subjects would continue to have a PTT tested every 6 hours until the PTT value falls between 40-45. All LDIVH subjects will have PTT values measured at least daily. This will continue until ICU discharge or a maximum of 28 days.

DRUG

Heparin

5000 units given subcutaneously three times a day until ICU discharge or a maximum of 28 days

Trial Locations (1)

80045

University of Colorado Hospital, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER

NCT01608906 - Using Intravenous Heparin Versus Standard of Care Subcutaneous Heparin to Prevent Clots After Surgery | Biotech Hunter | Biotech Hunter