Vilazodone for Treatment of Geriatric Depression

PHASE4CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Major Depressive Disorder
Interventions
DRUG

Vilazodone; Viibryd

Subjects randomized to receive vilazodone blindly will have incremental dose titration of 10mg per day for the 1st week; 20mg per day the 2nd week; 40mg per day for the 3rd-12th week. Doses of the drugs will be adjusted according to individual tolerability and safety.

DRUG

Paroxetine; Paxil

Subjects randomized to receive paroxetine blindly will have incremental dose titration of paroxetine 10mg per day for the 1st week; 20mg per day for the 2nd week; and 30mg per day for the 3rd-12 week. Doses of the drugs will be adjusted according to individual tolerability and safety.

Trial Locations (1)

90095

UCLA Semel Institute, Los Angeles

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Forest Laboratories

INDUSTRY

lead

University of California, Los Angeles

OTHER