NCT01605227 - Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100 | Biotech Hunter

Enrollment

1,028

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

September 30, 2014

Study Completion Date

March 31, 2015

Conditions

Prostate CancerCastration Resistant Prostate CancerPainProstatic Neoplasms

Interventions

DRUG

cabozantinib

Tablets taken orally once-daily

DRUG

prednisone

Taken twice a day orally. Commercially-obtained prednisone tablets will be over-encapsulated in order to blind identity.

Trial Locations (264)

7

Dublin

24

Dublin

1000

Brussels

1090

Vienna

Brussels

1100

Wein

1200

Brussels

2010

Darlinghurst

2031

Randwick

2076

Wahroonga

2145

Westmead

2193

Concord

2217

Kogarah

2444

Port Macquarie

2640

Albury

2820

Bonheiden

3128

Box Hill

3165

Bentleigh East

3500

Hasselt

3690

Wodonga

4000

Liège

4010

Linz

4101

South Brisbane

4102

Woolloongabba

4215

Southport

5000

Adelaide

5020

Salzburg

5037

Kurralta Park

6000

Perth

7000

Hobart

8800

Roeselare

9000

Ghent

9300

Aalst

10043

Orbassano

10065

New York

10126

Torino

11530

Garden City

12200

Berlin

12208

Albany

13055

Berlin

13273

Marseille

14076

Caen

15006

A Coruña

15706

Santiago de Compostela

16132

Genova

17033

Hershey

17604

Lancaster

19010

Bryn Mawr

20089

Rozzano

20132

Milan

20133

Milan

20162

Milan

20246

Hamburg

20817

Bethesda

21079

Dijon

21201

Baltimore

21204

Towson

22031

Fairfax

22399

Hamburg

22763

Hamburg

23601

Newport News

25030

Besançon

26100

Cremona

27100

Pavia

28007

Madrid

28040

Madrid

28041

Madrid

28050

Madrid

28100

Novara

28222

Majadahonda

28374

Pinehurst

28922

Madrid

29010

Málaga

29615

Greenville

30060

Marietta

30318

Atlanta

30607

Athens

30625

Hanover

31008

Pamplona

32796

Titusville

32806

Orlando

33006

Oviedo

33076

Bordeaux

33081

Aviano

33140

Miami Beach

33170

Pordenone

33332

Gütersloh

33401

West Palm Beach

33449

Wellington

33612

Tampa

34125

Kassel

34471

Ocala

35042

Rennes

35128

Padua

35205

Birmingham

37134

Verona

37421

Chattanooga

38126

Braunschweig

38320

San Cristóbal de La Laguna

40202

Louisville

40225

Düsseldorf

41013

Seville

41124

Modena

41701

Hazard

42103

Wuppertal

43221

Columbus

44805

Saint-Herblain

45219

Cincinnati

46009

Valencia

47014

Meldola

47900

Rimini

47906

Kempen

48121

Ravenna

48149

Münster

48202

Detroit

49509

Wyoming

49933

Angers

50010

Ames

50968

Cologne

51101

Sioux City

52062

Aachen

52074

Aachen

52100

Arezzo

54100

Nancy

54311

Green Bay

55455

Minneapolis

56126

Pisa

57123

Livorno

58501

Bismarck

59000

Lille

60126

Ancona

60488

Frankfurt am Main

60714

Niles

61401

Galesburg

63011

Clermont-Ferrand

65109

Jefferson City

65804

Springfield

66421

Homburg

67000

Strasbourg

67214

Wichita

68130

Omaha

68167

Mannheim

68506

Lincoln

69120

Heidelberg

69373

Lyon

69495

Pierre-Bénite

72000

Le Mans

72076

Tübingen

72100

Brindisi

72401

Jonesboro

72622

Nürtingen

73230

Kirchheim

75005

Paris

75010

Paris

75014

Paris

75015

Paris

75230

Paris

76022

Bedford

77024

Houston

77654

Offenburg

78041

Laredo

78217

San Antonio

79106

Amarillo

Freiburg im Breisgau

80045

Aurora

80131

Napoli

81675

München

83278

Traunstein

84112

Salt Lake City

85016

Phoenix

85255

Scottsdale

85710

Tucson

85925

La Roche-sur-Yon

90033

Los Angeles

90640

Montebello

90766

Fürth

91010

Duarte

92069

San Marcos

92093

La Jolla

92151

Suresnes

92270

Rancho Mirage

92346

Highland

92637

Weiden

92868

Orange

94301

Palo Alto

94574

St. Helena

94589

Vallejo

94805

Villejuif

97227

Portland

99204

Spokane

99508

Anchorage

06520

New Haven

06489

Southington

04412

Brewer

02114

Boston

02118

Boston

01844

Methuen

07601

Hackensack

08648

Lawrenceville

05405

Burlington

B-3000

Leuven

T2N 4N2

Calgary

V5Z 4E6

Vancouver

E1V 1Y3

Miramichi

B3H 1V7

Halifax

N6A 4L6

London

N4K 2J1

Owen Sound

H2L4M1

Montreal

G1R 2J6

Québec

01307

Dresden

Unknown

Cork

Galway

00128

Roma

00152

Roma

05100

Terni

1066 CX

Amsterdam

9713 GZ

Groningen

9728 NT

Groningen

2134 TM

Hoofddorp

3435 CM

Nieuwegein

6525 GA

Nijmegen

3045 PM

Rotterdam

3075 EA

Rotterdam

5042 AD

Tilburg

8025 AB

Zwolle

00716

Ponce

07010

Palma de Mallorca

08916

Badalona

08003

Barcelona

08023

Barcelona

08025

Barcelona

08035

Barcelona

08036

Barcelona

08908

L'Hospitalet de Llobregat

08243

Manresa

03016

Elche

SE 41345

Gotenborg

SE-20502

Malmo

SE-70185

Örebro

SE-17176

Stockholm

SE-90184

Umeå

SE 75185

Uppsala

SE-35185

Vaxjo

AB25 2ZN

Aberdeen

BA1 3NG

Bath

B15 2TH

Birmingham

BN2 5BE

Brighton

BS2 8ED

Bristol

CB2 2QQ

Cambridge

CF14 2TL

Cardiff

HU16 5JQ

Cottingham

EH4 2XU

Edinburgh

IV2 3UJ

Inverness

LA1 4RP

Lancaster

LS9 7TF

Leeds

SE1 9RT

London

W12 0HS

London

ME16 9QQ

Maidstone

CH63 4JY

Metropolitan Borough of Wirral

HA6 2RN

Northwood

PL6 8DH

Plymouth

S10 2SJ

Sheffield

S16 6YD

Southampton

SM2 5PT

Sutton