A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in Patients Aged 70 Years and Older With High Grade Gliomas (HGG)

PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

May 31, 2013

Primary Completion Date

October 31, 2016

Study Completion Date

November 30, 2017

Conditions
Glioblastoma
Interventions
DRUG

Hydroxychloroquine

200mg bd from 14 days post surgery until clinical or radiological progression

RADIATION

Radiotherapy

Short Course radiotherapy

Trial Locations (15)

LS9 7TF

St James's University Hospital, Leeds

LL18 5UJ

Glan Clwyd Hospital, Bodelwyddan

CB2 0QQ

Addenbrooke's Hospital, Cambridge

Unknown

Ninewells Hospital, Dundee

G12 0YN

Beatson West of Scotland Cancer Centre, Glasgow

GU2 7XX

Royal Surrey County Hospital, Guildford

NW1 2BU

University College Hospital, London

SE1 9RT

Guy's and St Thomas's Hospitals, London

w6 8RF

Charing Cross Hospital, London

M20 4BX

Christie Hospital, Manchester

TS4 3BW

James Cook University Hospital, Middlesbrough

NE7 7DN

Freeman Hospital, Newcastle

NR4 7UY

Norfolk & Norwich University Hospitals, Norwich

PR2 9HT

The Royal Preston Hospital, Preston

ST4 6QG

Royal Stoke University Hospital, Stoke-on-Trent

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cancer Research UK

OTHER

lead

University College, London

OTHER