Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

NAActive, not recruitingINTERVENTIONAL
Enrollment

1,746

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

July 31, 2018

Study Completion Date

November 30, 2026

Conditions
Severe Aortic Stenosis
Interventions
DEVICE

Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)

PROCEDURE

Surgical Aortic Valve Replacement (SAVR)

DEVICE

Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI)

Trial Locations (86)

10016

New York University School of Medicine, New York

10029

Mount Sinai School of Medicine, New York

10032

Columbia University Medical Center, New York

10075

Lenox Hill Hospital, New York

11030

North Shore University Hospital, Manhasset

11501

Winthrop University Hospital, Mineola

11576

St. Francis Hospital, Roslyn

14642

University of Rochester, Rochester

15213

University of Pittsburgh Medical Center, Pittsburgh

17043

Pinnacle Health Cardiovascular Institute, Wormleysburg

17822

Geisinger Medical Center, Danville

19104

University of Pennsylvania Health System, Philadelphia

20010

Washington Hospital Center, Washington D.C.

21205

The Johns Hopkins University, Baltimore

23226

Bon Secours St. Mary's Hospital, Richmond

23507

Sentara Cardiovascular, Norfolk

27157

Wake Forest University Health Sciences, Winston-Salem

27710

Duke University Medical Center, Durham

28203

Carolinas HealthCare System, Charlotte

30308

Emory University, Atlanta

30309

Piedmont Healthcare, Inc., Atlanta

33146

University of Miami, Coral Gables

33484

Delray Medical Center, Delray Beach

33756

Morton Plant Hospital, Clearwater

37232

Vanderbilt University Medical Center, Nashville

38120

Stern Cardiovascular, Memphis

43210

The Ohio State University, Columbus

43214

The OhioHealth Research Institute, Columbus

44106

University Hospitals Case Medical Center, Cleveland

45220

Good Samaritan Hospital, Cincinnati

46290

St. Vincent Heart Center of Indiana, Indianapolis

48202

Henry Ford, Detroit

48236

St. John Hospital & Medical Center, Detroit

49503

Spectrum Health Hospitals, Grand Rapids

50266

Iowa Heart Center / Mercy Medical Center, West Des Moines

53215

Aurora St. Luke's Medical Center, Milwaukee

55407

Abbott NW - MN Heart Institute Foundation, Minneapolis

55905

Mayo Clinic - St. Mary's Hospital, Rochester

60153

Loyola University of Chicago, Maywood

64111

Saint Luke's Hospital/MAHI, Kansas City

66160

University of Kansas Hospital, Kansas City

68124

Alegent Creighton Health Research Center, Omaha

70360

Cardiovascular Institute of the South, Houma

73120

Oklahoma Heart Institute, Oklahoma City

75093

The Heart Hospital - Baylor Plano, Plano

75226

Baylor Heart and Vascular Hospital, Dallas

77030

The Methodist DeBakey Heart & Vascular Center, Houston

79106

Universitäts-Herzzentrum Freiburg • Bad Krozingen, Bad Krozingen

84107

Intermountain Medical Center, Murray

85006

Banner Good Samaritan Medical Center, Phoenix

90033

Keck Medical Center of USC, Los Angeles

90048

Cedars-Sinai Medical Center, Hollywood

91101

Southern California Permenente Medical Group, Pasadena

92037

Scripps Green Hospital, La Jolla

94040

El Camino Hospital, Mountain View

94304

VA Palo Alto Health Care System, Palo Alto

94305

Stanford University Medical Center, Stanford

96813

The Queen's Medical Center, Honolulu

06102

Hartford Hospital, Hartford

06520-8047

Yale New Haven Hospital, New Haven

02215

Beth Israel Deaconess Medical Center, Inc., Boston

48109-5864

University of Michigan Health Systems, Ann Arbor

48201-2018

Detroit Medical Center, Detroit

08103

Cooper University Hospital, Camden

07960

Morristown Medical Center, Morristown

05401

University of Vermont, Burlington

Unknown

London Health Sciences Centre, University Hospital, London

Montreal Heart Institute, Montreal

Rigshospitalet, Copenhagen

Universitätsklinikum Bonn, Bonn

Deutsches Herzzentrum Muenchen, Munich

Amphia Hospital Breda, Breda

Medisch Centrum Leeuwarden, Leeuwarden

St. Antonius Hospital, R & D Cardiology, Nieuwegein

Erasmus Medical Center - Rotterdam, Rotterdam

Servicio de Cardiologia del Hospital Virgen de la Victoria, Málaga

Hospital Universitario Central de Asturias, Oviedo

Bern University Hospital, Bern

Universitatsspital Zurich, Zurich

Leeds General Infirmary, Leeds

M4N 3M5

Sunnybrook Research Institute, Toronto

M5G 2C4

Toronto General Hospital (University Health Network), Toronto

H3A 1A1

McGill University Health Center - Royal Victoria Hospital, Montreal

171 76

Karolinska Universitetssjukhuset Stockholm, Stockholm

LE5 4PW

Glenfield Hospital, Leicester, UK, Leicester

SW170QT

St. George's Hospital London, London

Sponsors
All Listed Sponsors
lead

Medtronic Cardiovascular

INDUSTRY

NCT01586910 - Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). | Biotech Hunter | Biotech Hunter