NCT01574651View on ClinicalTrials.gov

The Effect of QVA149 on Health Related Quality of Life in Patients With Chronic Obstructive Pulmonary Disease (COPD)

PHASE3CompletedINTERVENTIONAL
Enrollment

934

Participants

Timeline

Start Date

May 31, 2012

Primary Completion Date

April 30, 2013

Study Completion Date

April 30, 2013

Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG

QVA149

QVA149 110/50µg, once daily (q.d.) is administered via a single-dose dry powder inhaler

DRUG

Placebo to tiotropium

Placebo to tiotropium capsules daily (q.d.) for inhalation, delivered via proprietary inhaler (Handihaler®). Placebo tiotropium inhalation capsules were matched in size and color to tiotropium 18 μg q.d. inhalation capsules

DRUG

Placebo to formoterol

Placebo to formoterol capsules twice daily (b.i.d) delivered via Aerolizer® device. Placebo formoterol inhalation capsules were equally matched in size, shape and color to formoterol 12 μg b.i.d. inhalation capsules.

DRUG

Tiotropium

Tiotropium 18µg, once daily is administered via the manufacturer's proprietary inhalation device.

DRUG

Formoterol

Formoterol 12µg, twice daily is administered via the manufacturer's proprietary inhalation device.

DRUG

Placebo to QVA149

Placebo to QVA149 is administered via a single-dose dry powder inhaler. Placebo QVA149 inhalation capsules were equally matched in size, shape and color to QVA149 110/50 μg q.d. inhalation capsules

Trial Locations (144)

10115

Novartis Investigative Site, Berlin

10367

Novartis Investigative Site, Berlin

10717

Novartis Investigative Site, Berlin

10789

Novartis Investigative Site, Berlin

10969

Novartis Investigative Site, Berlin

12043

Novartis Investigative Site, Berlin

12099

Novartis Investigative Site, Berlin

12165

Novartis Investigative Site, Berlin

12203

Novartis Investigative Site, Berlin

12687

Novartis Investigative Site, Berlin

13057

Novartis Investigative Site, Berlin

13086

Novartis Investigative Site, Berlin

13156

Novartis Investigative Site, Berlin

13465

Novartis Investigative Site, Berlin

13507

Novartis Investigative Site, Berlin

14050

Novartis Investigative Site, Berlin

14059

Novartis Investigative Site, Berlin

14467

Novartis Investigative Site, Potsdam

14469

Novartis Investigative Site, Potsdam

14478

Novartis Investigative Site, Potsdam

14712

Novartis Investigative Site, Rathenow

15562

Novartis Investigative Site, Rüdersdorf

16515

Novartis Investigative Site, Oranienburg

16816

Novartis Investigative Site, Neuruppin

17166

Novartis Investigative Site, Teterow

18273

Novartis Investigative Site, Güstrow

20354

Novartis Investigative Site, Hamburg

20357

Novartis Investigative Site, Hamburg

21680

Novartis Investigative Site, Stade

22299

Novartis Investigative Site, Hamburg

22502

Novartis Investigative Site, Geesthacht

22527

Novartis Investigative Site, Hamburg

22880

Novartis Investigative Site, Wedel

22947

Novartis Investigative Site, Großhansdorf

23558

Novartis Investigative Site, Lübeck

23858

Novartis Investigative Site, Reinfeld

24534

Novartis Investigative Site, Neumünster

24837

Novartis Investigative Site, Schleswig

28844

Novartis Investigative Site, Weyhe

30163

Novartis Investigative Site, Hanover

30317

Novartis Investigative Site, Hanover

30419

Novartis Investigative Site, Hanover

31134

Novartis Investigative Site, Hildesheim

31224

Novartis Investigative Site, Peine

32423

Novartis Investigative Site, Minden

33617

Novartis Investigative Site, Bielefeld

34121

Novartis Investigative Site, Kassel

34346

Novartis Investigative Site, Hannover Münden

35037

Novartis Investigative Site, Marburg

Novartis Investigative Site, Marburg

36039

Novartis Investigative Site, Fulda

37075

Novartis Investigative Site, Göttingen

37269

Novartis Investigative Site, Eschwege

38820

Novartis Investigative Site, Halberstadt

39261

Novartis Investigative Site, Zerbst

39387

Novartis Investigative Site, Oschersleben

40489

Novartis Investigative Site, Düsseldorf

40878

Novartis Investigative Site, Ratingen

41462

Novartis Investigative Site, Neuss

42117

Novartis Investigative Site, Wuppertal

42651

Novartis Investigative Site, Solingen

42665

Novartis Investigative Site, Solingen

44135

Novartis Investigative Site, Dortmund

44787

Novartis Investigative Site, Bochum

45138

Novartis Investigative Site, Essen

45276

Novartis Investigative Site, Essen

45879

Novartis Investigative Site, Gelsenkirchen

47057

Novartis Investigative Site, Duisburg

47798

Novartis Investigative Site, Krefeld

48145

Novartis Investigative Site, Münster

48147

Novartis Investigative Site, Münster

48431

Novartis Investigative Site, Rheine

49074

Novartis Investigative Site, Osnabrück

51069

Novartis Investigative Site, Cologne

51429

Novartis Investigative Site, Bergisch Gladbach

51605

Novartis Investigative Site, Cologne

51643

Novartis Investigative Site, Gummersbach

52349

Novartis Investigative Site, Düren

53119

Novartis Investigative Site, Bonn

53123

Novartis Investigative Site, Bonn

53879

Novartis Investigative Site, Euskirchen

55116

Novartis Investigative Site, Mainz

55131

Novartis Investigative Site, Mainz

56068

Novartis Investigative Site, Koblenz

57072

Novartis Investigative Site, Siegen

57537

Novartis Investigative Site, Wissen

58452

Novartis Investigative Site, Witten

58507

Novartis Investigative Site, Lüdenscheid

58706

Novartis Investigative Site, Menden

59065

Novartis Investigative Site, Hagen

59174

Novartis Investigative Site, Kamen

60389

Novartis Investigative Site, Frankfurt

60596

Novartis Investigative Site, Frankfurt

63263

Novartis Investigative Site, Neu-Isenburg

63571

Novartis Investigative Site, Gelnhausen

63739

Novartis Investigative Site, Aschaffenburg

64625

Novartis Investigative Site, Bensheim

65428

Novartis Investigative Site, Rüsselsheim am Main

66111

Novartis Investigative Site, Saarbrücken

66539

Novartis Investigative Site, Neunkirchen

66740

Novartis Investigative Site, Saarlouis

68165

Novartis Investigative Site, Mannheim

69115

Novartis Investigative Site, Heidelberg

69117

Novartis Investigative Site, Heidelberg

69168

Novartis Investigative Site, Wiesloch

76224

Novartis Investigative Site, Singen

80335

Novartis Investigative Site, München

80539

Novartis Investigative Site, München

81677

Novartis Investigative Site, München

82131

Novartis Investigative Site, Gauting

83209

Novartis Investigative Site, Prien A. Chiemsee

84307

Novartis Investigative Site, Eggenfelden

86156

Novartis Investigative Site, Augsburg

86825

Novartis Investigative Site, Bad Wörishofen

86899

Novartis Investigative Site, Landsberg

89073

Novartis Investigative Site, Ulm

89231

Novartis Investigative Site, Neu-Ulm

89269

Novartis Investigative Site, Vöhringen

91052

Novartis Investigative Site, Erlangen

91126

Novartis Investigative Site, Schwabach

91154

Novartis Investigative Site, Roth

91301

Novartis Investigative Site, Forchheim

91315

Novartis Investigative Site, Höchstadt an der Aisch

93093

Novartis Investigative Site, Donaustauf

96049

Novartis Investigative Site, Bamberg

96515

Novartis Investigative Site, Sonneberg

97616

Novartis Investigative Site, Bad Neustadt an der Saale

99817

Novartis Investigative Site, Eisenach

01307

Novartis Investigative Site, Dresden

04207

Novartis Investigative Site, Leipzig

03050

Novartis Investigative Site, Cottbus

04552

Novartis Investigative Site, Borna

09130

Novartis Investigative Site, Chemnitz

04509

Novartis Investigative Site, Delitzsch

01069

Novartis Investigative Site, Dresden

06108

Novartis Investigative Site, Halle

06333

Novartis Investigative Site, Hettstedt

01917

Novartis Investigative Site, Kamenz

04103

Novartis Investigative Site, Leipzig

04275

Novartis Investigative Site, Leipzig

04357

Novartis Investigative Site, Leipzig

04758

Novartis Investigative Site, Oschatz

01445

Novartis Investigative Site, Radebeul

06682

Novartis Investigative Site, Teuchern

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY