Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

PHASE4CompletedINTERVENTIONAL
Enrollment

549

Participants

Timeline

Start Date

April 3, 2012

Primary Completion Date

May 22, 2014

Study Completion Date

May 22, 2014

Conditions
Attention-deficit/Hyperactivity Disorder
Interventions
DRUG

Lisdexamfetamine dimesylate

Daily oral dosing in the AM ranging from 30- 70 mg. 4 week forced dose titration, 2 week dose maintenance

DRUG

Methylphenidate Hydrochloride

Daily oral dosing in the AM ranging from 18-72 mg. 4 week force dose titration, 2 week dose maintenance

DRUG

Placebo

Daily oral dosing in the AM for 6 weeks

Trial Locations (95)

10023

Brain Resource Center, New York

10029

Mount Sinai School of Medicine/Dept of Psychiaatry, New York

15236

Klinik Fur Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie, Frankfurt

19380

University Services, West Chester

20852

Marc Hertzman, MD, PC, Rockville

22415

Kinderarztpraxis Dr. Kaiser und Dr. MarineBe, Hamburg

22903

University of Virginia Child and Family Psychiatry Clinic, Charlottesville

27705

Duke University medical Center/ Duke ADHD Program, Durham

28401

PMG Research of Wilmington, Wilmington

29812

Rainbow Research, Inc., Barnwell

30328

Atlanta Institute of Medicine & Research, Inc, Atlanta

32055

Sarkis Clinical Trials, Lake City

32256

Clinical Neuroscience Solutions, Inc, Jacksonville

32751

Florida Clinical Research Center, LLC, Maitland

32763

Medical Research Group of Central Florida, Orange City

32806

Clinical Neuroscience Solutions, Inc., Orlando

Compass Research, LLC, Orlando

33013

Amedica Research Institute, Inc, Hialeah

33143

Miami Research Associates, South Miami

33161

Scientific Clinical Research, Inc., North Miami

33169

Prevention & Strengthening Solutions, Inc., Miami

33613

Stedman Clinical Trials, Tampa

34201

Florida Clinical Research Center, LLC, Bradenton

36303

Harmonex Neuroscience Research, Inc., Dothan

38119

Clinical Neuroscience Solutions, Inc., Memphis

42301

Pedia Research, LLC, Owensboro

43210

The Ohio State University Nisonger Center, Columbus

45219

University of Cincinnati College of Medicine/UCPC, Cincinnati

47630

Pedia Research, LLC, Newburgh

48083

Behavioral Medical Center - Troy, Troy

48307

Rochester Center for Behavioral Medicine, Rochester Hills

48314

Clinical Neurophysiology Services, PC, Sterling Heights

60048

Capstone Clinical Research, Libertyville

60563

Baber Research Group, Naperville

60608

Clinical Research Center, University of Illinois at Chicago, Chicago

63301

St. Charles Psychiatric Associates - Midwest Research Group, Saint Charles

63368

Psychiatric Care & Research Center, O'Fallon

64118

Comprehensive Psychiatric Associates, Gladstone

66211

Psychiatric Associates, Overland Park

68159

Zentralinstitut fur Seelische Gesundheit, Mannheim

68198

University of Nebraska Medical Center Dept Of Psychiatry, Omaha

68526

Premier Psychiatric Research Institute, LLC, Lincoln

70114

Louisiana Resarch Associates, Inc., New Orleans

72211

Clinical Study Centers, LLC, Little Rock

74104

Tulsa Clinical Research, LLC, Tulsa

75231

FutureSearch Trials of Dallas, LP, Dallas

75234

Research Across America/Psychiatric Medical Associates, Dallas

77007

Bayou City Research, Houston

77008

Claghorn-Lesem Research Clinic, Ltd., Houston

77074

Clinical Trial Network, Houston

77081

Texas Center for Drug Development, Inc., Houston

77090

Red Oak Psychiatry Associates, PA, Houston

77098

Houston Clinical Trials, LLC, Houston

78229

Clinical Trials of Texas, Inc., San Antonio

Univ of Texas Health Science Center at San Antonio, San Antonio

79104

Universitatsklinikum Freiburg, Freiburg im Breisgau

79423

Westex Clinical Investigations, Lubbock

80112

IMMUNOe International Research Center, Centennial

80910

MCB Clinical Research Centers, LLC, Colorado Springs

84015

Ericksen Research and Development - Westside Medical, Clinton

85719

Center for Advanced Improvement, Tucson

87109

Albuquerque Neuroscience, Inc., Albuquerque

89128

Center for Psychiatry & Behavioral Medicine, Inc., Las Vegas

90274

Peninsula Research Associates, Rolling Hills Estates

91950

Synergy Clinical Research Center, National City

91978

Encompass Clinical Research, Spring Valley

92054

Pacific Sleep Medicine, A Medical Corporation, Oceanside

92108

PCSD - Feighner Research, San Diego

92251

Sun Valley Research Center, Imperial

92324

Shanti Clinical Trials, Colton

92595

Elite Clinical Trials, Wildomar

92868

Neuropsychiatric Research Center for Orange County, Orange

94143

University of California, San Francisco, San Francisco

96047

Schwerpunktpraxis fur Entwicklung und Lernen, Bamberg

97030

Cyn3rgy Research, Gresham

97070

Medizinisches Studienzentrum Wurzburg, Würzburg

97210

Oregon Center for Clinical Investigations Inc, Portland

Summit Research Network, Portland

97301

Oregon Center for Clinical Investigations, Inc, Salem

98007

Northwest Clinical Research Center, Bellevue

98033

Eastside Thereapeutic Resource, Kirkland

98104

Summit Research Network (Seattle), LLC, Seattle

99202

Rockwood Clinic, P.S., Spokane

06320

Coastal Connecticut Research, LLC, New London

08002

Center for Emotional Fitness, Cherry Hill

07856

The NeuroCognitive Institute, Mount Arlington

02886

Omega Medical Research, Warwick

B4N 4K9

True North Clinical Research, Kentville

L1N 2L1

The Kids Clinic, Whitby

H-1021

Vadaskert Gyermekpszichiatriai Korhaz es Szakambulancia, Budapest

H-5700

Bekes Megyei Pandy Kalman Korhaz, Gyula

H-7632

Pecsi Megyei Jogu varos Egyesitett Egeszsegugyi Intezmenyek, Pécs

H-6725

Szegedi Tudomanyegyetem, Szeged

411 19

Gillbergcentrum, Gothenburg

163 74

PRIMA Barn-och Vuxenpsykiatri Jarva, Spånga

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Shire

INDUSTRY