"CMV Antiviral Prevention Strategies in D+R-Liver Transplants (CAPSIL)"

PHASE4CompletedINTERVENTIONAL
Enrollment

205

Participants

Timeline

Start Date

October 29, 2012

Primary Completion Date

June 22, 2018

Study Completion Date

June 22, 2018

Conditions
Cytomegalovirus Infection
Interventions
DRUG

Valganciclovir

Valganciclovir, 900 mg given orally once daily to all Prophylaxis group subjects for 100 days post transplantation as prophylaxis. Valganciclovir, 900 mg given orally twice daily to Preemptive Therapy group subjects as a PET only after a positive CMV PCR test and stopped after PCR is negative for 2 consecutive weeks.

Trial Locations (6)

90095-8358

Ronald Reagan University of California Los Angeles Medical Center, Los Angeles

30322-1013

Emory Clinic - Transplant Center, Atlanta

55905-0001

Mayo Clinic, Rochester - Infectious Diseases, Rochester

10029-6504

Mount Sinai School of Medicine - Medicine - Infectious Diseases, New York

15213-3403

University of Pittsburgh - Medicine - Infectious Diseases, Pittsburgh

98195-7110

University of Washington - Medicine, Seattle

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT01552369 - "CMV Antiviral Prevention Strategies in D+R-Liver Transplants (CAPSIL)" | Biotech Hunter | Biotech Hunter