IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

July 31, 2012

Primary Completion Date

December 31, 2013

Study Completion Date

August 31, 2014

Conditions
Acute PainHyperalgesia
Interventions
DRUG

IV acetaminophen

Total of 6 doses of 1,000 mg IV acetaminophen at the following time points: (1) immediately after anesthesia induction, but prior to the incision, (2) at the end of surgery with (3) four additional doses administered postoperatively in the ICU every 6 hours for the first 24 hours.

DRUG

Placebo

Total of 6 doses of 100 mL of normal saline at the following time points: (1) immediately after anesthesia induction, but prior to the incision, (2) at the end of surgery with (3) four additional doses administered postoperatively in the ICU every 6 hours for the first 24 hours.

Trial Locations (1)

98195

University of Washington Medical Center, Department of ANesthesiology and Pain Medicine, Seattle

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mallinckrodt

INDUSTRY

lead

University of Washington

OTHER

NCT01544062 - IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery | Biotech Hunter | Biotech Hunter